New Posts New Posts RSS Feed - Hormone Replacement
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Hormone Replacement
 Post Reply Post Reply
Author
  Topic Search Topic Search  Topic Options Topic Options
sarahbeard1 View Drop Down
Newbie
Newbie


Joined: Apr 13 2010
Location: Salt Lake City
Status: Offline
Points: 5 		Post Options Post Options   Thanks (0) Thanks(0)   Quote sarahbeard1 Quote  Post ReplyReply Direct Link To This Post Topic: Hormone Replacement
    Posted: Apr 14 2010 at 4:58pm
I had my ovaries removed because of BRCA+, but I am only 33, and I am worried about osteoporosis. I am nervous about taking hormone replacement though, even though my oncologist gave me the go-ahead (he didn't seem too sure about his answer though). Has anyone taken hormone replacement after tnbc? Does anyone know if it increases the risk of recurrence for our type of cancer? And what about alternatives to hormones? Is there anything else that will prevent osteoporosis?

Thanks!
DX 7/2009 tnbc, IIb, BRCA1+, 4 dd AC, 2 dd taxol, 2 abraxane, bilateral mastectomy, 25 radiation, reconstruction, ovaries removed (brca1), hysterectomy. Age 32 at DX.
Back to Top
123Donna View Drop Down
Senior Member
Senior Member
Avatar

Joined: Aug 24 2009
Location: St. Louis, MO
Status: Offline
Points: 13510 		Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Apr 14 2010 at 8:46pm
Sarah,

I'm no expert and can only share with you what my ob/gyn said to me.  Even though I'm tnbc, he felt uncomfortable prescribing any type of hormone replacement therapy.  That was his opinion and other doctors may not see a risk.

If you're worried about osteoporosis, can you ask about a bisphosphonate drug, like Zometa or Boniva?

Donna
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
Back to Top
kirby View Drop Down
Senior Member
Senior Member


Joined: Oct 09 2007
Location: bay area,california
Status: Offline
Points: 1088 		Post Options Post Options   Thanks (0) Thanks(0)   Quote kirby Quote  Post ReplyReply Direct Link To This Post Posted: Apr 15 2010 at 1:40am
 Do you have a family history of osteoporosis? You have brought up a good point. I was somewhat concerned being thrown into chemopause being 12 years older than you.What about excersizing and weight training ? I have done both for years and did have a scan for bone density for a baseline a while after finishing chemo. I did just fracture my wrist [ falling in an excersize class LOL] and the recovery after getting the cast off has not been fun. I will revisit the whole bone density subject with my dr. next visit. You are wise to think of this. Although I am not sure HRT is the way to go and my onc also advised to never take it.
kirby

dx Feb. 2001. Age 44
Lumpectomy

2cm. no nodes stage 1 grade 3

4 rnds AC, 35 rads
Back to Top
sarahbeard1 View Drop Down
Newbie
Newbie


Joined: Apr 13 2010
Location: Salt Lake City
Status: Offline
Points: 5 		Post Options Post Options   Thanks (0) Thanks(0)   Quote sarahbeard1 Quote  Post ReplyReply Direct Link To This Post Posted: Apr 15 2010 at 2:22pm
Thanks for your input, ladies. I was searching on line and I found some helpful information (see below). I've decided to definitely not do HRT.

http://hormonenegative.blogspot.com/2009/08/is-hrt-safe-after-triple-negative.html

Friday, August 14, 2009

Is HRT safe after a triple-negative breast cancer diagnosis?

I got a question from a reader about taking hormone replacement therapy after a triple-negative breast cancer diagnosis—she is five years post-diagnosis disease free. (Yea for her.) I cannot find any research on this specific issue, but I did find a few related studies. Some of you might have similar questions, so I am posting this for others who might be in this situation.

• Some cases of HR- recur as HR+. Research on this was published in the Annals of Oncology. It was a pretty small sample, though—only 40 women initially.

• Estrogen can be a factor in the earliest formation of hormone-negative disease, according to research in the Journal of Steroid Biochemistry and Molecular Biology.

• The association between HRT use and breast cancer was the same for TNBC as for other forms of breast cancer in another study in the Annals of Oncology.

• Oral contraceptives were associated with a higher risk of TNBC in a study published in the journal Cancer Epidemiology, Biomarkers and Prevention.
DX 7/2009 tnbc, IIb, BRCA1+, 4 dd AC, 2 dd taxol, 2 abraxane, bilateral mastectomy, 25 radiation, reconstruction, ovaries removed (brca1), hysterectomy. Age 32 at DX.
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 12.01
Copyright ©2001-2018 Web Wiz Ltd.