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To Chemo or Not to Chemo

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Marla View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Marla Quote  Post ReplyReply Direct Link To This Post Posted: Nov 19 2009 at 10:40pm
Thank you all for your replies. All of your advice and encouragement helps tremendously. I've decide to go ahead with the chemo (TC 4 times), but I will do the treatments in Florida. Better to have sunshine than grey days. I don't look forward to it and I hate to think of what those toxins might be doing to the rest of my body. I don't believe there has been enough long term research done with this yet. But I guess I was just born in the wrong century. I'll keep pushing through, thanks again for all your kind words.
God bless all of you.
Marla
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unklez View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote unklez Quote  Post ReplyReply Direct Link To This Post Posted: Nov 19 2009 at 11:02pm
Originally posted by Marla Marla wrote:

Thank you all for your replies. All of your advice and encouragement helps tremendously. I've decide to go ahead with the chemo (TC 4 times), but I will do the treatments in Florida. Better to have sunshine than grey days. I don't look forward to it and I hate to think of what those toxins might be doing to the rest of my body. I don't believe there has been enough long term research done with this yet. But I guess I was just born in the wrong century. I'll keep pushing through, thanks again for all your kind words.
God bless all of you.
Marla

Dear Marla,
You seem at peace with your decision. Florida not Illinois is the place to get chemo during the winter months! TC 4 times should not be very hard. Please read up chemo tips here on this board and ask any and all questions so you can be well prepared for the process, side effects and ways to minimize the side effects.

Wife Dx: Jul/09. Age: 37. Size: 3cm. BRCA: -ve. Lumpectomy: Aug/09. Micromet 1/9 node. Chemo Start: Sep/09. E5103. DD ACB-> DD Abraxane (Taxol reaction). Zometa (S0307). Canadian Fraction Rads.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote MaryinSarasota Quote  Post ReplyReply Direct Link To This Post Posted: Nov 20 2009 at 6:22am
Marla,

Thank you for letting us know your decisions.  You have much support already but if there is anything I can help you with let me know. Today it will be sunny and 80. Yes, a good place to be.

Mary
53 @ Dx 5/08 Stage 1, grade 3, IDC 1.6 cm, 0 nodes, TNBC, lumpectomy, chemo TAC-6, radiation-34 12/18/08
NED-10/09, PBM w/TE recon. 7/10, removal of TE/infec 8/10. CT chest. Rec fat-graft & stem cells
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Carol (Tenn) Quote  Post ReplyReply Direct Link To This Post Posted: Nov 20 2009 at 7:14am
Marla,
Thank you for letting us know what you decided. Did you look into the possibility of getting Andramyacin with the T and C? Just wondering.
I pray that all will be well soon.
Love and Prayers,
Carol
St 2 Gr 3, A/C/T, DD
Radiation x35
Rec chest wall 07/09
Radiation x28
NED 10/24/11
NED 10/5/12
NED 03/15/13
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Post Options Post Options   Thanks (0) Thanks(0)   Quote scared Quote  Post ReplyReply Direct Link To This Post Posted: Nov 20 2009 at 10:51am
I've posted a reply earlier but I want to add another two cents into the ante.  A co-worker's wife has colon cancer stage 4.  She has had it for the last eight years.  I found out about her  cancer when I told him about my wife's breast cancer.

My co-worker's wife is named Lisa.  Lisa has had the cancer go to her bones, into her lungs, to her brain, and now it is back in her colon.  Her eldest daughter just married and another child is expecting their first grandchild next year.  

He believes his wife is hanging on to see that grandchild.  It seems we all need to decide what is important in our lives.  Lisa has had terrible effects of the treatments from all kinds of chemotherapies and radiation treatments but Life is what is important to her..

You need to decide what you are willing to endure to live.  Some will fight tooth and nail to see tommorrow and what treasures it could bring.  I wish you the best in making your decisions.

Dave
Wife diagnosed 7/08 stage 2B 4.78cm with 3 nodes. 15 weeks of Adriamycin and Cytoxin, Mastectomy, 12 weeks of Taxol, and 6.5 weeks of radiation.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote lisa k Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 12:03am
I read your post hoping to find an answer to my own question! I just had a lump. Tues 11/17. I have been diagnosed w/ stage 1 invasive dcis and TNBC my path on my lymph came back today neg. my non- invasive part of my cancer measured 0.2 but my invasive portion was the size of a clemetine orange (forgot to ask actual size today - was happy to just hear that margins were clear)! Is chemo the only answer...my surgeon said she could not give me a definite yes or no I must talk to an oncologist to get her opinion... any thoughts?????
 
Thanks,
Lisa
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kirby View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote kirby Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 1:06am
Lisa,
 
Tell us more of the path report or findings. I don't think I followed it correctly. Did you have DCIS in addition to a lump the size of a clementine? Stage 1 is usually 2 cm or less and no node involvement. [ 2cm is about the size of a grape]
 
Glad your margins were clear and sounds like no node invovlvement either.
TN responds well to chemo, so is our main form of ammo seeings that we don't have drugs such as herceptin, armidex, tamoxifan. Those only work with other receptor status.
kirby

dx Feb. 2001. Age 44
Lumpectomy

2cm. no nodes stage 1 grade 3

4 rnds AC, 35 rads
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Post Options Post Options   Thanks (0) Thanks(0)   Quote SagePatientAdvocates Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 8:28am
Dear Maria,

I am sorry about your dx and hope the chemo goes well for you. I believe you are wise to follow your doctor's advice.

I have a question, though...do you have a family history of cancer on either your mom or dad's side?

If you do I think you should consider speaking to a Certified Genetic Counselor to see if you should be tested for the BRCA mutation. You can find a CGC in your area through this website

www.nsgc.org

If you are near the Tampa area I know Moffitt has several good CGCs.

Perhaps, you have been tested already? I didn't see that in any of your posts or Kim's. 

good luck to you....

all the best,

Steve

p.s. Lisa, has anyone mentioned BRCA to you?
I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates
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Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 1:11pm
Hi Lisa,
 
Here are some links to help you understand more about TNBC.
 
 
 
 
 
 
 
 
Check the TNBC News/Resource section of the forum as there is alot of information for TNBC.
Stage 2 2003
Stage 1 2007
BRCA 1+
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Post Options Post Options   Thanks (0) Thanks(0)   Quote lisa k Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 2:30pm
I wrote a brief message last night about my cancer let me follow-up w/ more details.


I am a 44 years old and was diagnosed on 10/26/08:
Ductual carcinoma insitu / invasive
Stage 1
Triple Negative
size of cancer = 0.2cm

invasive component grade 2
in-situ component grade 3

My Ki-67 = 5%

I had a wide incision lumpectomy w/ a sential node biopsy on 11/17. My margins came back clear and my sential node biopsy came back clear.

My surgeon cannot determine if chemo will be needed, she said it is a tough call that will be have to be determined by the oncologists.

I have a strong history of breast cancer but the BRCA 1 and BRCA 2 that my mom had performed had the results of NO MUTATION DETECTED. My mom had DCIS in 2007 in her right breast that resulted in a mastectomy and reoccurence in 2009 of tubualr in her left breast that was treated w/ a lumpectomy - mom my is in her mid 60's. My grandmother had a bi-lateral mastectomy  - her first occurence was when she was 47 (her first breast was removed) and then reoccurence 2 years later and her other breast was removed- we do not know what type of breast cancer she had. She passed away in her mid 80's of bone cancer.

I am so unsure of what my treatment will be and I was just wondering what any of you survivors think or would recommend. My worse fear is REOCCURENCE not CHEMO.

Thank you in advance for any help/ suggestions or words of wisdom.

Lisa K.
Illinois
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trip2 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 2:48pm
Hi Lisa,
 
First of all your ki-67 number is good.  Most of ours are quite high. 
This shows the aggressiveness of our tumor.
 
I will give you some links for TNBC recurrence.
 
 
 
 
Mine came back after 4 years but mine was invasive.


Edited by trip2 - Nov 21 2009 at 2:49pm
Stage 2 2003
Stage 1 2007
BRCA 1+
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Marla View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Marla Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 5:27pm
Hi
I'm trying to get my act together to get of town on Monday. Saying good-bye for 4-6 months to my kids and especailly my grandkids is a very difficult emotional rollercoaster. It's hard to say Happy Thanksgiving, Merry Christmas, Happy New Year, Happy Valentine's Day, Happy Birthday and maybe Happy Easter. It just makes me cry. I know they will visit, don't know if it's a good idea to have visitors under the age of 5 in my weaken condition of being able to fight off infection. We will just have to see how I react to the chemo.
 
I'm going wig shopping Monday morning with both of my girls. A couple a freinds said I ought to try being a redhead - been a blond all my life. We will see!
 
Carol - My Onc determined the course of chemo according to the NCCN guidelines. Andramyacin was one of the options. We decided to not use that because I have a history of heart issues in my family history. Father died at age 56 of a heart attack and my brother died the same at age 47.  Andramyacin can sometimes be difficult on your heart.
 
Steve - I have no history of any types of cancers in my family. My Onc said that a BRAC test would be benefical for both of my daughters. And also for me, if I do test positive we may discuss removing my ovaries after treatment as a precautionary measure. Often if TNBC spreads and reoccurs it manifests in the ovaries. Surely at my age I don't need those any more - especally if they could cause problems.
 
Thanks everyone. My treatments won't start until about Dec 15th -so I'll keep looking for your support! God Bless!
 
Marla
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Marla Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 5:40pm

Lisa

I'm so new to all of this, you likely know more from your Mom and Grandmother. But I have researched and researched - chemo seems to be the only postive choice for TNBC. There is alot of wacky stuff out there, but not recommended by any credible medical source. My surgeon wouldn't make the call for chemo either, it's not their forte. No matter how many times I read and reread my dx it just doesn't change or get any better. They tell us we are "lucky" because we have found it early.
 
So go with your feelings and do what you need to do. I'm very much afraid of chemo, but I don't see any other path at this point. Who knows what might be developed by the time I have reoccurence. That is if this governement allows futher research! There's another "lucky" thing - we got this disease before socialized medicne controls our decisions!
 
Keep reading this site, the information is vast and better than talking to any Doc. But always ask your doctors about what you learn or have questions about.
 
Good Luck, I'll be going through this with you.     - Marla
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Carol (Tenn) Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 7:19pm
Pam,
What is ki-67? Where do I find that on my test results? That's a new one on me..
 
See new guys.....never to late to learn!!!
St 2 Gr 3, A/C/T, DD
Radiation x35
Rec chest wall 07/09
Radiation x28
NED 10/24/11
NED 10/5/12
NED 03/15/13
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Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 7:39pm
Hi Carol,
 
It should be on your copy of your path report.  Hope you have one.
 
Stage 2 2003
Stage 1 2007
BRCA 1+
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Post Options Post Options   Thanks (0) Thanks(0)   Quote lisa k Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 7:55pm
Pam,
The lower the percent the better...the average percent is 20% according to what my pathologist wrote on my report.
 
Check out yours - good luck,
Lisa
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Carol (Tenn) Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 8:00pm

I've got the report and I can't find any mention of that test anywhere??? Is it normal procedure?

St 2 Gr 3, A/C/T, DD
Radiation x35
Rec chest wall 07/09
Radiation x28
NED 10/24/11
NED 10/5/12
NED 03/15/13
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Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 8:13pm
Carol,
 
It should be on there but possibly not.  Thought it usually is recorded on your initial path report.
 
I know, the higher the more aggressive, mine the second time was around 80 can't remember the first time.
Hey I don't get as much info on my path as many others do, give it another look.
 
If you can't find it ask your Onc next time you go in, he would know.  And tell him you want a copy!
Stage 2 2003
Stage 1 2007
BRCA 1+
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Carol (Tenn) Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 8:24pm
Pam
 
I looked and looked but nothing...What CEA????
 
I will ask onc about it on my next visit..Dec 8th
St 2 Gr 3, A/C/T, DD
Radiation x35
Rec chest wall 07/09
Radiation x28
NED 10/24/11
NED 10/5/12
NED 03/15/13
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Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 21 2009 at 8:27pm
Carol,
 
What do you mean "what CEA??"
Stage 2 2003
Stage 1 2007
BRCA 1+
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