TNBC Talk - Xeloda - Oral Chemo

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Xeloda - Oral Chemo - Any Suggestions?

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URL: http://forum.tnbcfoundation.org/forum_posts.asp?TID=13748
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Topic: Xeloda - Oral Chemo - Any Suggestions?

Posted By: Barbs
Subject: Xeloda - Oral Chemo - Any Suggestions?
Date Posted: Oct 27 2020 at 10:17pm

I am a 70 year old woman diagnosed in March of this year with TNBC in the left breast with 3 involved nodes. I had 12 Taxol/Carboplatin chemos and 4 A/C chemos that resulted in significant shrinkage of the tumors. Two weeks ago I had a lumpectomy and 16 nodes removed. Pathology of the breast tissue showed no cancer cells and clear margins. However 2 of the 16 nodes that were removed tested positive for cancer cells. Today my oncologist gave me a grade of B+ with regard to success. However, he is now recommending an 8 course treatment of an oral chemo drug Xeloda (Capecitabine) over a span of 6 months. Has anyone else had experience with this drug? Side effects can be pretty bad - is it worth the time, expense and pain. A recent study indicates a 10-20% improvement in odds of non recurrence.

Replies:

Posted By: SagePatientAdvocates
Date Posted: Oct 28 2020 at 9:18am

Dear Barbs,

I don't think anyone here can tell you whether the Xeloda "is it worth the time, expense and pain?" We, including me, are not medical professionals and I suggest you speak to a
Breast Medical Oncologist to get a second opinion on your case, if you are willing to, rather than relying on anyone here.

Depending on where you live, your insurance coverage and willingness to travel I may be able to find someone you can speak to who is knowledgeable about TNBC and
may reaffirm the Xeloda suggestion or not.

I have helped many who have taken Xeloda and here is a link from Mayo Clinic that describes the drug and if you scroil down you will see many side effects listed. If you decide to take the drug you may experience some of the side effects, but, often, not all of them. From my experience you may experience some of them but everyone is different and the side effects are often different for each person.

Here is the link-

https://www.mayoclinic.org/drugs-supplements/capecitabine-oral-route/side-effects/drg-20062501?p=1" rel="nofollow - https://www.mayoclinic.org/drugs-supplements/capecitabine-oral-route/side-effects/drg-20062501?p=1

wishing you good luck no matter what you decide.

Please send me a Private Message and I will send you my phone number if you would like to talk but, again, I will not tell you whether or not to take Xeloda or any other drug.

warmly,

Steve

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I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates

Posted By: 123Donna
Date Posted: Oct 28 2020 at 9:26am

Hi Barbs,

There have been several members take Xeloda after neoadjuvant chemo. I'll post the threads on the subject. My only thought about this disease is we only get one chance to try and kill this beast the first time.

https://forum.tnbcfoundation.org/xeloda-after-neoadjuvant-chemotherapy-and-surgery_topic13153_page1.html" rel="nofollow - https://forum.tnbcfoundation.org/xeloda-after-neoadjuvant-chemotherapy-and-surgery_topic13153_page1.html

https://forum.tnbcfoundation.org/xeloda-after-act-chemo-mastectomy-and-radiation_topic13703_post135284.html" rel="nofollow - https://forum.tnbcfoundation.org/xeloda-after-act-chemo-mastectomy-and-radiation_topic13703_post135284.html

https://forum.tnbcfoundation.org/has-anyone-taken-xeloda-after-ac-t_topic13652_post134914.html" rel="nofollow - https://forum.tnbcfoundation.org/has-anyone-taken-xeloda-after-ac-t_topic13652_post134914.html

Donna

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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

Posted By: Debaura211
Date Posted: Dec 16 2020 at 8:42pm

Is anyone doing metronomic xeloda - about 1/2 the dosage of the 2 week on/one off 6 month regiment, but for a year?
Deborah