TNBC Talk - Grade 1 or 2 tnbc

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Grade 1 or 2 tnbc

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Forum Name: TNBC Talk
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URL: http://forum.tnbcfoundation.org/forum_posts.asp?TID=13672
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Topic: Grade 1 or 2 tnbc

Posted By: Suebhs
Subject: Grade 1 or 2 tnbc
Date Posted: Mar 07 2020 at 2:25pm

It seems like most tnbc is grade 3. Is grade 1 or 2 less common? Just wondering because mine was a grade 2.

Replies:

Posted By: 123Donna
Date Posted: Mar 08 2020 at 1:13am

Sue,

You are correct, most TNBC is grade 3. TNBC is fast growing so it's usually a grade 3 upon diagnosis. With your grade 2, it's a better prognosis.

Tumor grades are usually classified as:

Grade 1. The tumor cells look the most like normal tissue and are slow-growing (well-differentiated).

Grade 2. The tumor cells fall somewhere in between grade 1 and grade 3 (moderately-differentiated).

Grade 3. The tumor cells look very abnormal and are fast-growing (poorly-differentiated).

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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

Posted By: Suebhs
Date Posted: Mar 08 2020 at 11:06am

So it's a good thing! I'll take it, lol. Thanks for sharing the info, Donna.

Posted By: Plume
Date Posted: Mar 09 2020 at 10:07am

Yes, Donna, thanks from me too. I love and can understand the concise way you have described the different grades. Mine was, as you say, cells looked very abnormal and were poorly-differentiated. In fact, my biopsy report used those very words (except that the words were in French!)

Posted By: Penny
Date Posted: Mar 09 2020 at 11:27am

thanks.

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DX IDC, TNBC 12/7/16 (age 55), Stage 1a Grade 2, .6cm, 0/1 nodes, Lumpectomy & node dissection 12/22/16, BRCA1&2 negative 1/23/17 Chemo TC. Chemo completed 3/28/17. 30 RADs completed 6/6/17.