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What about Alternative/Unconventional Treatment?

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Topic: What about Alternative/Unconventional Treatment?
Posted By: Matt.Velez
Subject: What about Alternative/Unconventional Treatment?
Date Posted: Dec 17 2019 at 2:21pm
I am wondering if anyone has information or has experienced alternative/unconventional treatment outside of the US (i.e. Mexico, Germany, Thailand, Spain, Switzerland, etc.).  I know there are places in Arizona (eg. Envita) that practices non-traditional treatment that incorporates (Vitamin C therapy, Ozone therapy, Hyperthermia, Dendridic Cell Vaccines, and other alternative methods).  They also tend to focus on Detoxification, Emotional/Spiritual, and Nutrition as a way to treat the Whole Body and not just the cancer.  

Though not cheap and out of pocket in most cases, I hear there are many success stories for all types of cancer - but not sure about TNBC. 

Any info???



Replies:
Posted By: 123Donna
Date Posted: Dec 18 2019 at 7:49am
I followed a young woman on FB who was metastatic TNBC.  She was a young mother with children and had traditional treatment and then towards the end sought unconventional treatment in Mexico costing $xxxxx of money per treatment.  Sadly, it did not stop the cancer.


-------------
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15



Posted By: Matt.Velez
Date Posted: Dec 18 2019 at 11:12am
Wow. So sad to hear.  I understand that the earlier the treatment the better, but even still... nothing is guaranteed.  Thanks for sharing.  


Posted By: 123Donna
Date Posted: Dec 18 2019 at 7:48pm
Matt,

If you are on FB, you can read her story and see what treatments she tried:

Fighting Cancer with Sarah Amento




-------------
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15



Posted By: Matt.Velez
Date Posted: Dec 19 2019 at 11:32am
What a Warrior Spirit!!! Even though things turned the way they did, I so appreciate that she did what she felt was best for her situation. She did it her way!


Posted By: Plume
Date Posted: Dec 19 2019 at 3:40pm
Hi Matt
This was sent to me by a friend who had had 3 cancers himself.  It was the early days after my diagnosis and I was researching different methods of treatment.  You might find this article interesting
https://www.statnews.com/2017/08/29/cancer-treatment-alternative-medicine/" rel="nofollow - https://www.statnews.com/2017/08/29/cancer-treatment-alternative-medicine/   I wish you both all the very best!


Posted By: Matt.Velez
Date Posted: Dec 20 2019 at 10:30am
Plume - thanks for sharing.  Definitely a sad outcome.  What I think gets overlooked when speaking on alternative treatment is that alternative should actually mean “integrative” so that people get the best of both worlds. It is clear that straight chemo is hard physically, emotionally, mentally, etc. but by integrating non-traditional aspects that work to boost the whole body’s immune system through proper nutrition, emotional healing, spiritual practice, and exercise... I think there is a good chance to manage side effects and develop a stronger mindset. With that, I say do both if possible.  It is also known that the later and the more progressive the cancer, the more difficult this becomes, but ultimately I do think there is a place for alternative treatment - especially when doctors give you no other choice but chemo and clinical trials, which often do not work either. 


Posted By: FullTilt
Date Posted: Dec 23 2019 at 10:49pm
This treatment is going to change the way cancer is managed - In my opinion! I hope it can help women with like it has the first two patients! I am so excited to see this monoclonal antibody progress so rapidly. It is stoping the spread of the cancer and shrinking even eliminating the tumors all with no serious side effects. This press release out just today.

https://www.globenewswire.com/news-release/2019/12/23/1963963/0/en/CytoDyn-Reports-Early-But-Strong-Positive-Clinical-Responses-for-Two-Patients-One-in-Metastatic-Breast-Cancer-and-One-in-Metastatic-Triple-Negative-Breast-Cancer-Trials.html " rel="nofollow - https://www.globenewswire.com/news-release/2019/12/23/1963963/0/en/CytoDyn-Reports-Early-But-Strong-Positive-Clinical-Responses-for-Two-Patients-One-in-Metastatic-Breast-Cancer-and-One-in-Metastatic-Triple-Negative-Breast-Cancer-Trials.html  ;

The company is in the process of screening and enrolling 20 more patients right now and will have more results in a few weeks. If you have metastatic breast cancer call the company and get involved in this trial!

Pacific Hematology Oncology Associates 
New Patient Coordinators:
David Ruiz at (415) 417-3337
Mary Grace at (415) 923-3105

Patient referrals directly to:  
Dr. Milana Dolezal 
Main telephone:  (415) 923-3012 
2100 Webster Street, Suite 220
San Francisco, CA 94115



Posted By: 123Donna
Date Posted: Dec 23 2019 at 11:11pm
Matt,

Check out the long term survivor story link at the bottom.


Originally posted by 123Donna 123Donna wrote:

There is someone who is a patient of Dr. Chue on this forum.  Here's a link to the discussion:

http://forum.tnbcfoundation.org/any-long-term-survivors_topic13518_post133985.html" rel="nofollow - http://forum.tnbcfoundation.org/any-long-term-survivors_topic13518_post133985.html

[QUOTE=HopefulToday]I am a patient of Dr Chue's. He is a kind and gentle human being. Please google him and see what others have written. When you speak with him, you will think you are the only patient he has. I can't recommend him enough. I saw 6 oncologists before I went with Dr Chue and Lifespring Cancer Care.

Case report of long-term survival with metastatic triple-negative breast carcinoma

Treatment possibilities for metastatic disease


  https://journals.lww.com/md-journal/Fulltext/2019/04190/Case_report_of_long_term_survival_with_metastatic.63.aspx" rel="nofollow - https://journals.lww.com/md-journal/Fulltext/2019/04190/Case_report_of_long_term_survival_with_metastatic.63.aspx



-------------
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15



Posted By: FullTilt
Date Posted: Dec 23 2019 at 11:29pm
Donna, 

Great link including some description of immunotherapy. I wanted to give you some more information on what I think is the best immunotherapy treatment and show you some of the research supporting this monoclonal antibody that inhibits the CCR5 receptor and helps the body fight the cancer.

CCR5 , Cancers , Leronlimab.... 


1.) CCR5 makes cancers cells metastasize ... 

........A.) By calcium channel signalling on CCR5 on cancer cells , witch is important to produce metastasis. 
........B.) CCR5 makes tumors more aggressive , CCR5 center cells cluster together in a different way witch enables the cancer cells to metastasize. 
.........C. ) once cancer cells enter to bloodstream and ( and thus become ) CTC, being CCR5 + guides them to the most dangerous and deadly possible sites : Brain , bones , other organs , .. 

Leronlimab block all this... 
Papers: 

https://content.equisolve.net/_5dde3bf0adc36825aed9c147d6727220/cytodyn/db/252/2425/pdf/3+ccr5+breast.pdf" rel="nofollow - https://content.equisolve.net/_5dde3bf0adc368...breast.pdf  

https://content.equisolve.net/_5dde3bf0adc36825aed9c147d6727220/cytodyn/db/252/2429/pdf/5+Review+of+%E2%80%9Conci-2-e23660.pdf%E2%80%9Dreview.pdf" rel="nofollow - https://content.equisolve.net/_5dde3bf0adc368...review.pdf  

https://content.equisolve.net/_5dde3bf0adc36825aed9c147d6727220/cytodyn/db/252/2427/pdf/4+ccr5+prostate.pdf" rel="nofollow - https://content.equisolve.net/_5dde3bf0adc368...ostate.pdf  

https://cancerres.aacrjournals.org/content/canres/early/2019/07/10/0008-5472.CAN-19-1167.full.pdf" rel="nofollow - https://cancerres.aacrjournals.org/content/ca...7.full.pdf  




2.) CCR5 activates DNA mechanism.... 


...........cancer cells recuperate much faster after chemotherapy , becoming resistant to treatment 

Leronlimab is blocking that. 

Papers: 
https://content.equisolve.net/_5dde3bf0adc36825aed9c147d6727220/cytodyn/db/252/2433/pdf/7+CCR5-+DDR.full.pdf" rel="nofollow - https://content.equisolve.net/_5dde3bf0adc368...R.full.pdf  
https://www.cell.com/stem-cell-reports/pdf/S2213-6711%2819%2930145-6.pdf" rel="nofollow - https://www.cell.com/stem-cell-reports/pdf/S2...0145-6.pdf  

3.) Regulate body anti-tumor response .. 

...........A. ) there is polarization of macrophages with CCR5 inhibitors. 
process by witch macrophages adopt different functional programs.. 

M0--uncommitted macrophages .. 
M1--classically activated , produce pro-inflammatory process and irritation of immune system , important in the host defense against pathogens . 
M2--alternatively activated, turning on constructive process, like wound healing , producing anti-inflammatory cytokines. 
And all this help to produce necrosis of tumors. 

............B. ) From Dr Patterson we also know that CCR5 is expressed on the population of immune cells call T regulatory cells witch inhibits response to cancers . 

Papers: 
https://www.cell.com/cancer-cell/pdf/S1535-6108%2816%2930102-7.pdf" rel="nofollow - https://www.cell.com/cancer-cell/pdf/S1535-61...0102-7.pdf  

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983686/pdf/ijms-19-01477.pdf" rel="nofollow - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC...-01477.pdf  
https://www.frontiersin.org/articles/10.3389/fimmu.2018.02629/full" rel="nofollow - https://www.frontiersin.org/articles/10.3389/...02629/full  

4.) Leronlimab inhibits angiogenesis 

Recently we also learned from Dr Lindner pre-clinical study in colon cancer that Leronlimab inhibits angiogenesis , and is working on solid tumors with both high and low CCR5 expression.. 

Papers: 
https://www.ncbi.nlm.nih.gov/pubmed/25330803" rel="nofollow - https://www.ncbi.nlm.nih.gov/pubmed/25330803  
https://academic.oup.com/carcin/article/36/1/104/376718" rel="nofollow - https://academic.oup.com/carcin/article/36/1/104/376718  
https://www.cell.com/stem-cell-reports/pdf/S2213-6711%2819%2930145-6.pdf" rel="nofollow - https://www.cell.com/stem-cell-reports/pdf/S2...0145-6.pdf  
https://www.cytodyn.com/newsroom/press-releases/detail/346/cytodyn-sponsored-researchreaffirms-the-role-of-ccr5-in" rel="nofollow - https://www.cytodyn.com/newsroom/press-releas...of-ccr5-in  


5) CCR5 Promotes Cancer Recurrance 

Paper: 
https://elifesciences.org/articles/43653" rel="nofollow - https://elifesciences.org/articles/43653  

Node-Negative Overall Survival with ccr5 from Pestell paper Figure 1B 
https://content.equisolve.net/_5dde3bf0adc36825aed9c147d6727220/cytodyn/db/252/2433/pdf/7+CCR5-+DDR.full.pdf" rel="nofollow - https://content.equisolve.net/_5dde3bf0adc368...R.full.pdf  


Read More:  https://investorshangout.com/post/view?id=5506865#ixzz68zks9wva" rel="nofollow - https://investorshangout.com/post/view?id=5506865#ixzz68zks9wva



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