I am brand new to the forum, I so appreciate having this space to talk.
I am 52, diagnosed TNBC in April of this year. Grade 3, no staging done yet.
Did 1 round of AC in May, got approved for Keytruda, restarted chemo in June with Taxol/Carbo/Keytruda. 12 weekly cycles of that, then 1 more AC but tumour doubled in size, so chemo was stopped altogether.
Due to extreme hyperthyroidism, Keytruda is paused. Treating this with beta blockers which are working well so far.
Had another CT scan last week and waiting for results. Had another biopsy Monday and waiting for those results. Reason for this biopsy is because my onco said I may have a second cancer in that tumour OR it may be morphing into another cancer subtype.
Spoke with my surgeon yesterday and he said because tumour is 5cm, we must do a mastectomy, but until biopsy results come back, everything is up in the air as they may try another chemo on me if I present with different bio markers from the biopsy.
The waiting game is awful, as you all know and I feel so defeated with no chemo response.
My onco also said my tumour is very hard, and TNBC tumours are usually softer or squishy. Mine is like a ball and you can roll it around, which he was confused with too.
Thanks for reading. If anyone here has had chemo resistance, I’d appreciate hearing from you.
Lynda