New Posts New Posts RSS Feed - Lymphovascular Invasion
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Lymphovascular Invasion

 Post Reply Post Reply
Kmemeo View Drop Down

Joined: Oct 28 2020
Location: San Diego, Ca
Status: Offline
Points: 11
Post Options Post Options   Thanks (0) Thanks(0)   Quote Kmemeo Quote  Post ReplyReply Direct Link To This Post Topic: Lymphovascular Invasion
    Posted: Jan 20 2021 at 1:16pm
Does anyone have LVI?  
I see that this has an even poorer survival.  I would like to know if anyone knows more about this. 

I just had an 8 week follow-up CT chest, abd, pelvis and PET after being on a clinical trial using paclitaxel and cirmtuzamab.  I had some nodes decrease and some increase, overall I am happy that it is not progressing at this time.  It WILL progress eventually (the next 2-6 cycles) according to the oncologist and then I will need to find another trial.  I was really hopeful until I met with the doctor. I am not sure it is because of the lymphovascular invasion that she is not as hopeful as I am.  Or if it is because of my biomarkers or genes don't have treatment options or clinical trials.  

I have 1% PDL1 on my Guardant of liquid biopsy, not sure which. My lumpectomy tissue is being examined from 2 years ago to get more information on that.  

My Genes are:
PGR, ESR1 (both underexpressed)
CCNE1, MYC, MTDR (overexpressed)

Guardant 360 Biomarkers:
AR amplification  Medium
TP53 35%

TMB 4.78
DX: IDC 1.3 cm, stage 1C, grade 3, ki-67 87%, BRCA -, LX, ACT, radiation 5-12/18, age 47
Recurrence 10/20, lymph nodes in chest, mediastinum, mult bil lung nods
TX: paclitaxel and cirmtuzumab,trial.
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 12.01
Copyright ©2001-2018 Web Wiz Ltd.