Chemo after surgery/good Pathology results (PcR)

My wife didn't have a 100% PCR with neoadjuvant chemo, it reduced it by 75%, she has(had?) metaplastic/squamous/ stage 3A (actually I think it's 3C, despite them saying the chemo killed it in the lymph nodes, to me, it was in at least 4 nodes, not sure if that's to make us just feel better)
Anyway, the oncologist said it's "possible" the cancer that became resistant in the 4.5cm tumor, reduced to 1.5 cm was the "metaplastic part"
But maybe that's the stem-cell part?
Since my wife is finished, for now with treatments, it's not good for me to bring up the issue (yet)of since they sent out the tissue after surgery and did genectic testing (6 genes, all neg for mutations) why can't they come to a determination on the part of the tumor that's resistant, is this metaplastic/squamous, or stem cell part? Of course, this is WAY beyond my pay-grade, and perhaps expecting doctors and researchers to be God.



Edited by gordon15 - Apr 26 2016 at 6:24pm