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CTB
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Topic: 4 vs 6 chemo treatments Posted: Mar 24 2010 at 9:10pm |
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I am looking for some information from others who are currently undergoing chemo or have recently ended theri treatmnet about how many chemo cycles they had. I am 61 years old and was diagnosed in 12/09 with a 2.0 cm., Stage 1, grade 3 tumor and was Dx. with TNBC. I had a lumpectomy and SNB after Christmas with no lymph node involvement and clear margins. I have had 3 cycles of Cytoxin/Taxotere scheduled at 21 day intervals. I expect to have one more and when completed will have radiation. Recently I have spoken to others who have been treated for TNBC who feel anything less than 6 treatments is not adequate. I know that treatments change as trials and reserach are completed but I want to be as aggressive as possible to give me the best chance to not have a recurrence but I am certainly looking forward to being done with this phase of the treatment. I appreciate any information that others have to share. Thanks.
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jamo
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Posted: Mar 24 2010 at 9:24pm |
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I understand where you're coming from. I was diagnosed 6/08 TNBC. I was 44 at that time. 1.5 cm, grade 3, no lymph node involvement. Lumpectomy and 4 cycles of Cytoxin/Taxotere 3 wks apart and 33 rads. I'm doing fine but sometimes worry I haven't done enough. As I have educated myself more, I regret not being more aggressive. I had a second opinion from NorthwesternHospital/Chicago at that time and was offered to be in a clinical trial but turned it down. Sometimes I wished I would've done it, but I'm not going to live in the "should've" mind set though. Hopefully by eating very healthy and exercising and giving the rest to God, it won't show up somewhere else. If you do not think that you're getting enough treatment, let the Oncologist know now because once it's all completed, there's not much else you can do, but whatever you choose to do, try not to look back. Good luck.
Edited by jamo - Mar 24 2010 at 9:25pm
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dmwolf
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Joined: Jan 22 2009
Location: Berkeley, CA
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Posted: Mar 25 2010 at 12:15am |
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CTB, that's a good question. The clinical trial that compared AC to TC and found them equivalent or TC even a little better was I think just 4 rounds. But 2.0cm is on the border of being stage II and it is high grade. Hmmm....personally I would probably go with six, but I doubt there's any data to back up the choice one way or another. Actually, now that I think about it and re-read your post, I see that you didn't do dose dense either (every 2 weeks instead of every 3). I would definitely do them. Or at last get a second opinion on the question from a medical oncologist at a different hospital/institution. Good luck deciding, Denise
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DX 2/08@43 stg II IDC; gr2,0 nodes. Neoadj chemo, first ACx2 (fail) then CarboTaxotereX6(better). Lump, Rads done 11/08; Clodronate. False alarm queen: PetCT lung & TM marker. NED. PBM w/recon 9/10.
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Sugar77
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Posted: Mar 25 2010 at 11:34am |
CTB - I did TC x4 and am totally comfortable with it. My onc never mentioned doing 6 and I asked him half way through it he thought I should do more and he said no. My tumor was very small and I feel it was treated aggressively. Good luck in making your decision
Sherri
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DX IDC TNBC Oct. 27, 2009, age at diagnosis 45, Stage 1, Grade 3, <1 cm, 0/2 nodes, lumpectomy, Taxotere/CytoxanX4, finished Feb. 8, 2010, radiation completed Apr. 21, 2010.
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123Donna
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Location: St. Louis, MO
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Posted: Mar 25 2010 at 1:09pm |
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Hi,
I had TC X 4. I asked my onc if I should have more and she said no also. I'd ask you onc again if you're uncomfortable with only having 4 treatments or maybe get a second opinion. I know you don't want to have any regrets. Let us know what you decide.
Donna
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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09) 11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
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kirby
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Posted: Mar 25 2010 at 2:12pm |
CTB,
I only had 4 X AC , every 3 weeks, but that was years ago before they knew exactly what TN was . I was 44. I am not sure when they started treating it more aggressively but most with my tumor size [same as yours] are given DD and more chemo.
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kirby
dx Feb. 2001. Age 44 Lumpectomy
2cm. no nodes stage 1 grade 3
4 rnds AC, 35 rads
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Lillie
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Posted: Mar 25 2010 at 3:12pm |
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Hi CTB,
I understand your questioning. I had 4 dd AC bi-weekly and 4 dd taxol and gymzar bi-weekly (total of 8 cycles). But, I did not have radiation because I had a mastectomy and only 1 node slightly involved
Per my oncologist, I was staged IIb because the tumor was 2cm, 1 node positive, and triple negative. I had agressive chemo, but still wonder about not having radiation.
If you have doubts about the number of treatments you should certainly discuss it with your oncologist. At least you in a position to agree with the present protocol or discuss more treatments. Good Luck
Lillie
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Dx 6/06 age 65,IDC-TNBC Stage IIb,Gr3,2cm,BRCA- 6/06 L/Mast/w/SNB,1of3 Nodes+ 6/06 Axl. 9 nodes- 8/8 thru 11/15 Chemo (Clin-Trial) DD A/Cx4 -- DD taxol+gemzar x4 No Rads. No RECON - 11/2018-12 yrs NED
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TNBC_in_NS
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Joined: Jul 26 2009
Location: NS Canada
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Points: 2028
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Posted: Mar 25 2010 at 3:59pm |
Hi Christine and Welcome to our Web Site!
You will find the most gracious, intelligent and experienced people on this site who will be there to help you through your journey.
I had TC x 4 as well. My stats are in my signature. In Dec I completed 16 rounds of radiation. If you are wondering about your treatments, it is better to discuss this with your onc. They really do listen to us. A second opinion is also in order just for piece of mind fi you feel like they are not listening to you. I luckily did not have to do this but if I felt I needed more treatment, I certainly would have asked for it.
Good luck with your decisions and keep us posted as to what you have decided to do.
Your TNBC friend in NS, Helen
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Diag@57TNBC04/092.5cm Lquad 05/09 TCx4Radsx30CT03/01/10 FU03/31/10ClearBRCA- 01/2011 RTNBC BMX 06/14/2011~2013 clear
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tasoulla
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Posted: Mar 28 2010 at 10:11am |
Hi Kirby,
I wanted to ask you, back in 2001 when you had your treatment they didn't separate the breaast cancer tumours in TN? Did you received any hormone pills then?(or tamoxifen?).
Do you know now that you were TN?
All these 9 years did you take any supplements or pills?
All the best to you
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kirby
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Posted: Mar 28 2010 at 1:13pm |
tasoulla,
TN was not labeled when I was dx. I only knew I was negative for er, pr & her2. Herceptin was only given for metastatic disease and tamoxifen and such was for er, pr +. TN was known for what it wasn't.I only knew I was left out. There wasn't additional protection for me. On the one hand I was concerned but on the other I was so glad not to be taking any more meds and dealing with side affects.
All these 9 years I really haven't changed my lifestyle. I try to be consistent with taking vitamins. But go thru long stretches of not. If taken, I only do calcium, D, multi and maybe B or something for extra iron. I do run 2 miles daily and do weight training 2x a week [ unless I have a time crunch, then that goes]. I try to eat healthy [ but then I did before cancer too] but do like my food, more on the gourmet side, I like to cook. I am overweight [ middle age now and my cooking !].
The best to your mother. I hope she is doing well.
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kirby
dx Feb. 2001. Age 44 Lumpectomy
2cm. no nodes stage 1 grade 3
4 rnds AC, 35 rads
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Kellyless
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Posted: Mar 28 2010 at 1:27pm |
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CTB, since you are having these worries and second thoughts, I would suggest you seek out a second opinion from an oncologist that only treats breast cancer and that has extensive experience with TNBC. Now is the time to do everything you can to make you comfortable post treatment. We ALL worry post treatment, but your worries are starting so soon, I think you should address it and get that second opinion as quick as you can.
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IDC, 2.2 cm, Stage IIb,lumpectomy 1/30/09 ACx4,Tx4 36 rads 6/1/16 Local recurrence same breast, same spot 1.8cm Carb.4x every 3 wks, Taxol 12x once wk. Dbl Mast. PCR!! Reconstruction fail, NED!
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CTB
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Posted: Apr 02 2010 at 5:42pm |
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I wanted to thank everyone who replied and offered me their input. I have just returned home from my fourth and final TC cycle. I did get two additinal opinions from Oncologists at different hospitals. They all agreed with the 4 cycles of TC for my diagnosis and said that is the current standard of practice and there is just no evidence at this time that 6 is better then 4. The Clinical trial that was done comparing 4 cycles of AC to 4 cycles of TC was refered to by all 3. I am comfortable that I have received the tretament I needed and now it is on to Radiation in 3 weeks or so. This past week I started to have neuropathy in my toes and I hope it does not move into my fingers. My Oncologist recommended a B-Complex vitamin with Folic Acid. Any other suggestions will be most appreciated. Hapy Easter to all.
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123Donna
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Posted: Apr 02 2010 at 6:17pm |
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CTB,
Hi, I take B-6 100 mg twice a day. I was taking only one pill a day, but still have numbness in my fingertips and sometimes feet.
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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09) 11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
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trip2
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Posted: Apr 03 2010 at 12:07pm |
Hello and welcome.
Chemo induced peripheral neuropathy can be a problem for some. You may have a little or alot, it may stay for a short while or last indefinitely or come on later after treatment.
I take Neurontin 3 times a day. I had bad peripheral neuropathy after my second diagnosis of taking Taxotere x6. Some take Lyrica. These meds are adjusted as you take them to find a mg which will help. I had the numbness, off balance, terrible shooting pains in my thighs, my Neurontin makes a big difference.
Hopefully yours will pass quickly. 
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Stage 2 2003
Stage 1 2007
BRCA 1+
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