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Lightheaded after 1st AC

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    Posted: Mar 07 2013 at 10:22pm
I just had my first AC today.  (It was Dose Dense Adriamycin/Cytoxan.)  During the infusion, even before the Adriamycin or Cytoxan were administered I started feeling light headed and a little dizzy.  It continued to slowly get worse over the rest of the infusion time.  On the drive home I developed a headache behind my eyes.  The chemo nurse said she hadn't really heard of that as  a side effect so suggested I take a Lorazepam when I got home in case it was anxiety related.  After I took it I read the side effects sheet and realized that Lorazepam can CAUSE dizziness and lightheadedness.  I'm still experiencing that, but maybe it's now from the drug.  :)  About an hour after the Lorazepam, I felt the first twinges of nausea.  I took one of the pills right away, Prochlorperazine 10mg and tried to take a nap.  I dozed off and on for a couple hours, but woke up still feeling the same.  The nausea is worse and the headache is still there.  I just took two Tylenol for the headache and am waiting for them to kick in.  I've been drinking TONS of water, 5 1/2 24oz bottles so far today and I had hydration in my IV.  I don't think it can be dehydration related.  Anyone else experience anything like this?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote mainsailset Quote  Post ReplyReply Direct Link To This Post Posted: Mar 07 2013 at 10:44pm
Have you had a chance to check your BP? Getting a BP cuff and a personal thermometer are great things to have on hand at home and to use regularly. I had a similar experience and we found that my BP had shot through the roof. Easily addressed and once I was through with the chemo it levelled off. There's no reason why anyone going for chemo, particularly the first time, wouldn't experience panic and have a BP surge. I was told to refer to them as 'power surges' by a dear friend...they're the power surges of a warrior going into battle so it sounds like you're up to the challenge. Lots to get used to but you were smart to give the office a call and report the dizziness to them.
dx 7/08 TN 14x6.5x5.5 cm tumor

3 Lymph nodes involved, Taxol/Sunitab+AC, 5/09 dbl masectomy, path 2mm tumor removed, lymphs all clear, RAD 32 finished 9/11/09. 9/28 CT clear 10/18/10 CT clear
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Post Options Post Options   Thanks (1) Thanks(1)   Quote Grateful for today Quote  Post ReplyReply Direct Link To This Post Posted: Mar 07 2013 at 11:33pm
HOC,

1st.......glad your first chemo is completed.   Now, you and your team can tweak the plan for the
next time.....discuss with your oncologist and chemo nurse your 1st chemo experience and see what
they recommend for a better 2nd chemo.      
And many times, one finds the 2nd chemo better as many have more anxiety with the 1st chemo.   

Good that you informed your chemo nurse about how you felt.
Mainy gave some very good tips.
Thinking that since you said you felt light headed and a little dizzy before the adriamycin and cytoxan,
if your blood pressure was checked then, it probably was not too high or low or else they would
have mentioned it.
Sometimes, it is hard to find the cause of a lightheaded....difficult to describe sensation.
With an initial chemo, one has the factors of anxiety as well as the pre-chemo meds (and one of
those could be the cause and just need some adjusting).
Most likely, the light-headed feeling will be less or gone in the morning.   And if not, you can call your
   treatment team.....just to be sure.
Hydration is important. As you said you are well hydrated. If one is drinking mainly water, might be
     good to include some other liquids and variety of tolerated foods to maintain normal electrolyte
     balance (and you are probably already doing this.)
If you still have nausea in the morning, consider calling your provider and review when it started and
what you have done and what are the next best steps for YOU.

Hoping you have a good night's sleep.


With caring and positive thoughts,
Grateful for today............Judy


Edited by Grateful for today - Mar 08 2013 at 1:47am
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Post Options Post Options   Thanks (0) Thanks(0)   Quote HOC Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 12:48am
MainSailSet,

I DID have my BP checked while I was there.  It was 142/88, 141/88, and 155/?? right before I left.  The nurse wasn't at all concerned. The final one was after I stood up.  She was looking for a dip in blood pressure but said being high was fine. 

I'm going back in tomorrow for the Neulasta shot and IV hydration so I'll talk to them more then.  Thanks for your help!!


Edited by HOC - Mar 08 2013 at 12:49am
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Post Options Post Options   Thanks (0) Thanks(0)   Quote HOC Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 12:52am
I found out that I was given Aloxi in the IV for nausea and the most common side effect from it is headache.  Wish they would have told me that!  Maybe the lightheaded/dizziness was the onset of the headache. 
 
I called in to the Seattle Cancer Care Alliance about an hour ago to see if there was something else I should do.  I love that they're open until 10pm! They adjusted the way I was taking the meds at home (higher dose and regular schedule) and definitely recommended going in tomorrow for the hydration.  It was already on my schedule so that's not a problem.
 
Thanks again Everyone!!
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Post Options Post Options   Thanks (1) Thanks(1)   Quote overwhelmed Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 8:35am
I was also told that Aloxi can cause headaches.  This is the difficult part of chemo.  As you use one med to help with one side effect, it can create another one.  But, each cycle can be different, and one issue doesn't necessarily happen each time. 
As far as your blood pressure goes, I had high blood pressure for the year I was getting Avastin.  I felt that gave me a headache and created some minor issues with my vision, although I was told I wouldn't feel anything with high blood pressure (but I swear I did).  My numbers looked similar to yours, and the only time they got alarmed was when the bottom number went up to 100.  It went down pretty quickly, so nothing else was done. Otherwise they just watched. Now my blood pressure is back to normal.
 
Hang in there.  Stay hydrated, and eat whatever happens to sound good.  In a few days your first treatment cycle will be behind you. It is good that you are going in for fluids.  Hopefully, that will knock out that headache.
 
Lori
DX ILC TNBC 3/10 at 50, Stage IIb; Grade 3; 5.1 to 7 cm,SNB neg;TC-6 rnds, 30 rads, Avastin-18 rnds, BRAC 1&2-
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Post Options Post Options   Thanks (0) Thanks(0)   Quote HOC Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 10:47am
Thanks, Lori!
 
It's so helpful hearing from others who have been through it.  I know everyone is different, but a couple of us have to be similar at least, don't we??  Lol  A neighbor of mine ran out an got me Gatorade last night and I switched to that instead of water for awhile.  Seemed to help a bit with the nausea.  I doubled the Lorezapam and fell asleep on the couch within an hour.  This morning the nausea seems slightly better, but I still have the headache.  I took two Tylenol (nurse said it's okay, just no Advil, aspirin) and I have another glass of Gatorade.  Don't think I can eat anything yet.  I was going to go through a cookbook I was given called Eating Through Cancer.  It breaks everything down from what to eat the day before treatment, day of treatment, and day following as well as foods that help with various side effects.  As this is my first treatment, I'm not sure how helpful it's going to be, but it sure looks like an awesome book!
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Post Options Post Options   Thanks (1) Thanks(1)   Quote overwhelmed Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 11:04am
HOC,
I am glad the nausea is better.  Let's hope the headache follows.  I remember the feeling of just not being right those first few days.  I got that book too, and it's great.  I think in the end you just eat what sounds good when it sounds good.  I drank a lot of Ensure for the protein.  So, Ensure, or Carnation Instant Breakfast might help.   Food tasted different, and I couldn't take anything spicy.  Ketchup was spicy.  I also found that when I wanted something, I wanted it, but the next day the thought of it would make me sick.  I still can't eat eggplant because I had it in a pasta dish and got sick afterwards. 
 
It sounds terrible, but I made it through each cycle and found a way to get enough good food in me so that I was fine. 
 
One last warning, and it's not a fun one.  The meds can cause constipation, but as the week wore on I found that I had diarrhea.  It was my body's way of getting the chemo out of me.  I never wanted to be too far from a bathroom.  That would last about a day, and then things would be back to normal.  So, I added immodium to the many drugs I carried around in the week following treatment.
 
The good thing is, as I write this, it all seems so long ago.  It's difficult, but every day you are one day closer to the end of it. 
 
Rest, hydrate, rest . . .
DX ILC TNBC 3/10 at 50, Stage IIb; Grade 3; 5.1 to 7 cm,SNB neg;TC-6 rnds, 30 rads, Avastin-18 rnds, BRAC 1&2-
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Post Options Post Options   Thanks (1) Thanks(1)   Quote acb Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 2:44pm
HOC
This is my first post, but I have been lurking for a couple years and have found good advice.
I also had headaches from Aloxi.  I am prone to getting migraines.  Ask your Dr. if you can try another anti nausea med in your pre treatment.  I was able to use Kytril without getting headaches or nausea, but he may have another one that you could possibly try if he is open to using another drug.
You can get through this.  Remember to go at your own speed and get plenty of rest.
Dx 7/2010 IIa, Gr 3, 0 SNL, 3 cm, R BMX with delayed reconstruction, spindle cell metaplastic, DD ACT, BRCA neg
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Post Options Post Options   Thanks (0) Thanks(0)   Quote BamaRachel Quote  Post ReplyReply Direct Link To This Post Posted: Mar 08 2013 at 10:42pm
Ask your nurses about the infusion rate, i.e., can it be slowed down.  I started almost immediately experiencing headache/tingling during my first Cytoxin treatment, told the nurse about it, she slowed the rate of infusion down some and never had another problem with it.  

So glad your first treatment is behind you.  Hope you get to feeling better soon.

DX 7/5/11, TN Invas; Lump w/clear marg., 7/21/11; Stage 2A. Grade 3, 2.6 c; 0/6 nodes; TX 8/22/11 4DD E/C; 4Taxotere; Chemo ended 1/3/12; 33 Radiation Treatments, ended 3/15/12.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote HOC Quote  Post ReplyReply Direct Link To This Post Posted: Mar 11 2013 at 11:33am
Thanks, BamaRachel,
 
When I went in for hydration on Friday (and the Neulasta) the nurse said something about asking to slow the infusion rate next time, too.  I'll definitely ask about that!  It was a bad weekend, but at least I'm feeling more myself today.  :)
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Post Options Post Options   Thanks (1) Thanks(1)   Quote denise07 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 11 2013 at 8:41pm
HOC,
Glad your feeling better today!
DX Idc 10/07,st2,gr3,2/6 lymphnodes
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Grateful for today Quote  Post ReplyReply Direct Link To This Post Posted: Mar 14 2013 at 11:09pm
HOC,

Hope you are continuing to feel better after your 1st AC.
You did all the right things.......informed your providers, tried various things and got additional     
information.......and now you and your providers can tweak your pre-chemo and chemo plan for
a better next chemo experience.   Pat yourself on the back........you knew your body and kept on
top of things until things started to improve.


With caring and positive thoughts,
Grateful for today.............Judy


PS: Had posted some thoughts/considerations on chemo on your other thread:
      http://forum.tnbcfoundation.org/topic10978_post111229.html#111229
      If that is too much to read, just disregard.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote HOC Quote  Post ReplyReply Direct Link To This Post Posted: Mar 18 2013 at 12:52pm
Thanks, Judy!  I've been feeling great.  I can almost forget that I'm doing chemo.  If it weren't for Thursday looming ahead of me!  Actually, I'm dreading number 2 far less than the first one.  I think between the information I've gotten from this site and the nurse, and knowing more what to expect, a lot of the anxiety has gone away.  Keeping my fingers crossed...
 
Thanks for the info and support!!
Heather
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Post Options Post Options   Thanks (0) Thanks(0)   Quote HOC Quote  Post ReplyReply Direct Link To This Post Posted: Mar 22 2013 at 5:05pm
So, yesterday was my 2nd round of AC and again I got lightheaded and dizzy.  It was definitely from the Aloxi since that was all that was running besides saline.  This time the nurse wasn't willing to let it go.  She got on the internet and started doing some research since dizziness wasn't listed as a possible side effect on their site.  Well, on the manufacturers web site she found a clinical trial where 688 people were given the drug and 6 of them reported dizziness as a side effect.  A little less than 1%.  Figures I'd be in the 1%!  Anyway, next time they're not going to do Aloxi.  I think it'll just be Zofran and I'll have to keep it up at home to prevent the nausea.  The nice thing about Aloxi is that it lasts 3 days.  I had one other little mishap yesterday.  When they accessed my port for the blood draw, they covered it with the bandage for sensitive skin.  By the time I was ready to go home, my chest was all red, especially under the bandage.  I had to stay late to consult with a dr in case it was a problem with the port itself.  However, after replacing the cover with a regular one (NOT sensitive skin) and giving me Benadryl through the IV the redness was much better.  Guess I not only have a rare allergy to Aloxi, but am also sensitive to the sensitive skin bandages!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Natalie Quote  Post ReplyReply Direct Link To This Post Posted: Mar 22 2013 at 5:41pm
HOC,
Oi at least you and the nurse figured it out. I had so many side affects, the nurse always acted like she had never heard of them before. Coming here to this site I was validated every time.
Natalie
TNBC stage1 size 1.8, grade3 no nodes 4/11 Lumpectomy 5/11 4cycles DD A/C 4cycles DD Taxol. Double Mastectomy 12/11 BRCA all neg
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