New Posts New Posts RSS Feed - Tigris Pharma Presents Results of BC Research
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Tigris Pharma Presents Results of BC Research

 Post Reply Post Reply
Author
trip2 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Jun 03 2007
Location: Under Palm Tree
Status: Offline
Points: 8549
Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Topic: Tigris Pharma Presents Results of BC Research
    Posted: May 01 2009 at 5:26pm
http://www.medicalnewstoday.com/articles/148412.php

Edited by trip2 - May 01 2009 at 6:42pm
Stage 2 2003
Stage 1 2007
BRCA 1+
Back to Top
SagePatientAdvocates View Drop Down
Senior Advisor
Senior Advisor
Avatar

Joined: Apr 15 2009
Status: Offline
Points: 4748
Post Options Post Options   Thanks (0) Thanks(0)   Quote SagePatientAdvocates Quote  Post ReplyReply Direct Link To This Post Posted: May 02 2009 at 8:19pm
Thanks for posting this Pam...I hope this drug makes it through Phase II and
particularly Phase III...I think it is important to keep on top of these studies because you never know when someone may be admitted to a certain trial when everything else has failed..

I know you put in a lot of work researching new studies/drug trials etc. for our community and I wanted to sincerely thank you for all your hard work.
It is all very much appreciated and I am glad you are posting things in this forum. It is my belief that even if there is not a lot of discussion about some of the studies/trials you never know what information resonates with someone and may become important to them..so thanks again..

all the best,

Steve
I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates
Back to Top
LRM216 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 18 2009
Location: Marietta, GA
Status: Offline
Points: 1196
Post Options Post Options   Thanks (0) Thanks(0)   Quote LRM216 Quote  Post ReplyReply Direct Link To This Post Posted: May 03 2009 at 12:39am
Thanks so much Pam for passing this on to us.  Sure hope it can help us triple n's as we so need it!  I have just started my chemo last Thursday (AC + T) and am relatively new to all this, I do have a question.  How does one know if their triple neg is basal or non basal.  I do not see that anywhere on my path reports.  Is that an additional testing that must be done?  I have read that most triple neg is basal like but not all are.  How do you find out?
Linda - diagnosed at age 62
Diag 2/23/09 IDC 1.2 cent. IDC right breast,Stage 1, Grade 3,0/1 nodes - Triple Neg
4 DD AC every two weeks, 1 Dd Taxol, then 3 Taxotere every three weeks - rads x 33
Back to Top
NancyJane View Drop Down
Senior Member
Senior Member
Avatar

Joined: Aug 25 2008
Location: Key Largo, FL
Status: Offline
Points: 241
Post Options Post Options   Thanks (0) Thanks(0)   Quote NancyJane Quote  Post ReplyReply Direct Link To This Post Posted: May 03 2009 at 4:17am
LRM:
I too had the same question.  I called the pathologist who did my original path report and requested my tumor be further tested to reveal if it is basal type or not.  The testing was done, and my cancer is of the basal group.
 
I never actually spoke to the pathologist.  I left a voice mail message and also explained what I wanted to the receptionist.  It took about 2-3 weeks to have this done from the time I first called untill I received the appended pathology report.  Good luck!
Nancy Jane
41yr dx 7/25/08
Lumpectomy and ax node disection (38 nodes, all clean!) 8/12/08
T2 grd 3, N0, TN IDC
BRCA1+
ACx4,Tx12 10/08-3/09
prophylactic hyst, ooph,mast & one-step recon 3/30/09
Back to Top
LRM216 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 18 2009
Location: Marietta, GA
Status: Offline
Points: 1196
Post Options Post Options   Thanks (0) Thanks(0)   Quote LRM216 Quote  Post ReplyReply Direct Link To This Post Posted: May 03 2009 at 4:39am
Much thanks, Nancy Jane.  I go for bloodwork Thursday, will try to ask about having it tested.  All good wishes to you.
 
Linda
Linda - diagnosed at age 62
Diag 2/23/09 IDC 1.2 cent. IDC right breast,Stage 1, Grade 3,0/1 nodes - Triple Neg
4 DD AC every two weeks, 1 Dd Taxol, then 3 Taxotere every three weeks - rads x 33
Back to Top
trip2 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Jun 03 2007
Location: Under Palm Tree
Status: Offline
Points: 8549
Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: May 06 2009 at 7:02pm
Linda the test for basal is a separate test, I have never seen it on my pathology reports either and when I asked my Onc at the time he didn't know what the word Basal meant.Unhappy
 
You are correct according to what I read most but not all tn's are basal.
One member has posted that she was not basal.  Her Onc had had the test done during the original diagnosis.  Wish they all would but guess it is considered an extra test for now.
Stage 2 2003
Stage 1 2007
BRCA 1+
Back to Top
LRM216 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 18 2009
Location: Marietta, GA
Status: Offline
Points: 1196
Post Options Post Options   Thanks (0) Thanks(0)   Quote LRM216 Quote  Post ReplyReply Direct Link To This Post Posted: May 07 2009 at 8:35am

Well, I saw my onc's PA today for a 1 wk blood check since my first A/C last Thursday and my Neulasta shot last Fri. a.m.  Unfortunately, I have an extremely low blood counts from the first chemo.  She says that this does in fact happen to some women (from the adriamycin) but she did not want me to go back to work today or tomorrow.  I am to go back this Monday a.m. for another blood test.  She said the Neulasta shot doesn't always kick in on some women until day 11/12.  I guess Monday will tell if I get my second chemo next Thursday (the 14th) or not.  However, now that I have rambled on about my 0.7 wbc count and my 69,000 rbc count, I did ask about the basal type cell test and she said they do not order it as the AC +T that I am getting is as stong as she feels comfortable in giving me.  I am 62 work full time at a large law firm, but otherwise, have always been very healthy.  So I guess that was a no for the testing.  She saw no purpose in it as the chemo would not differ whether it was basal or non basal.  I admire the poster that was able to call the path herself and order it.  That just doesn't happen in Atlanta, GA.  The only way you get into pathology on your own is on a gurney!

Linda

Linda - diagnosed at age 62
Diag 2/23/09 IDC 1.2 cent. IDC right breast,Stage 1, Grade 3,0/1 nodes - Triple Neg
4 DD AC every two weeks, 1 Dd Taxol, then 3 Taxotere every three weeks - rads x 33
Back to Top
Jessie View Drop Down
Senior Member
Senior Member
Avatar

Joined: Aug 07 2007
Location: North Carolina
Status: Offline
Points: 515
Post Options Post Options   Thanks (0) Thanks(0)   Quote Jessie Quote  Post ReplyReply Direct Link To This Post Posted: May 07 2009 at 10:12am
Linda,
 
I don't know what test or what part of the pathology determined basal/non-basal, but on the first meeting, after my surgery, with the oncologist, she told me that my tumor was non-basal and that was an advantage, even tho it was still TN and grade 3.
 
Maybe that's the lucky break that has kept mine from recurring in these now 3 years !  I assume I'm also BRCA negative. Haven't had the testing, but I have very little history of cancer in my family --- we seem to prefer strokes and heart attacks.  Confused 
 
Jessie    
IDC,Stage I,Grade 3,dx 4/06
dbl mast 5/06,
systemic MRSA post surgery
septic shock, heart attack
triple bypass 1/07
no chemo due to infections and heart issues
so far NED!
Back to Top
trip2 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Jun 03 2007
Location: Under Palm Tree
Status: Offline
Points: 8549
Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: May 07 2009 at 10:23am

Well IMHO I disagree with the PA saying there was no purpose to this test.  I think the test should be done on all tri negs.

I know from reading studies that they are looking into the various factors of basal/non basal and there are some differences.  I would love to have that test.

Thanks for the update Linda, so sorry to hear about the low counts.  Hope that changes soon.  Is there something they told you to do, eat , drink?
 
Best wishes
Stage 2 2003
Stage 1 2007
BRCA 1+
Back to Top
LRM216 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 18 2009
Location: Marietta, GA
Status: Offline
Points: 1196
Post Options Post Options   Thanks (0) Thanks(0)   Quote LRM216 Quote  Post ReplyReply Direct Link To This Post Posted: May 07 2009 at 11:45am
Can't eat any salads, can't eat any fruits or veggies that can't be peeled - and I can not go to work today or tomorrow - and then no children around or not allowed to go into stores, crowds, etc.  So I am just staying home and will go back Monday a.m. for new blood work and hope that it will then be better.  God , I hate all of this crap.  I am supposed to call her asap if I get a fever that reaches 100 and then to emergency to be put in isolation!  Never opted for any of this to happen - and this was only my first chemo (AC +T).  Should bode well for the future!
 
Linda
Linda - diagnosed at age 62
Diag 2/23/09 IDC 1.2 cent. IDC right breast,Stage 1, Grade 3,0/1 nodes - Triple Neg
4 DD AC every two weeks, 1 Dd Taxol, then 3 Taxotere every three weeks - rads x 33
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 12.01
Copyright ©2001-2018 Web Wiz Ltd.