Connie, thank you so much for posting the article on Xeloda. It's interesting that Dr. Harris mentioned in the teleconference there is trial evidence that Avastin and Xeloda wasn't effective. But, at what dose? For my liver mets, I am on a lower daily dose of Xeloda with no break and 50 mg of Cytoxan. I have an Avastin infusion every 2 weeks. Next week will be my second one. This is based on a European trial published in the Journal of Clinical Oncology. It just gets so confusing at times doesn't it? What was really interesting is that Xeloda becomes 5Fu. I had that as part of my treatment last year. Thanks, Cornelia