Immunotherapy has not shown the promise we've hoped for.
“Immunotherapy presents tremendous promise for cancer treatment, but we haven’t yet found a way to make it widely effective,” said senior author Robert D. Schreiber, PhD, the Andrew M. and Jane M. Bursky Distinguished Professor. “It still doesn’t work for many patients, particularly for common cancers, such as breast or prostate. We want to understand why they are ineffective in these cases so we can make better therapies. Our research suggests that immunotherapy is likely to be more effective when a vaccine is used alongside checkpoint inhibitors.”