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Adrea
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Topic: FEC and Taxotere Posted: Dec 28 2007 at 6:10am |
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I am interested in opening a discussion with ladies who have received or are receiving the chemo combination of FEC and Taxotere.
I have completed 1 FEC treatment with little to no side effects except a little "foggy" on days 3-5. Not so much that I couldn't continue to complete all daily activities including driving, just a little "off center."
One unexpected side effect of the "E" is a slightly pink tinge to my blonde hair - a little gift of color before it probably goes away.
I was dx 11/7/07, lump and SNB 11/27/07, IDC, 2.8cm, TN, node negative, stage IIB, grade 3.
I retired June 30, 2007, so do not have to worry about trying to work - what a blessing in this fight. I am also blessed with a very large loving and caring family to support me.
Happy New Year,
Adrea
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Nikol
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Posted: Dec 28 2007 at 1:51pm |
Dear Adrea,
I received also this chemo combination. I started with neoadjuvant FEC (4x), after surgery had 2x FEC and after radiotherapy 4x Taxotere treatments. After the first chemo treatments I didnīt have big problems but later was it harder because I got more tired. The side effects of FEC were problems with veins. After Taxotere I had neutropenia and needed antibiotica. It caused also a pain in fingers when I touched something with hands. Some of the side effects can pass very quickly and others after some months after your treatment.
After taking the red Epirubicin I had also for short time red cheeks and we joked about it with my family. What is positive in your case that you have a family support, you know about this forum and donīt need to worry about your work. This will help you to go through the treatment.
I wish you and all the members a happy New Year.
Nikol
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marreb
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Posted: Jan 01 2008 at 12:49pm |
Hi Adrea,
I also received FECx6. Was dx 01/07, IDC,2.4cm.0/7 nodes, stage 2. I am now 6 months passed my last chemo, still not back to work yet, quite tired. During treatment, my worst side effects were heartburn and constipation. I am still having problems with my arm from the red devil, epirubicin, the same as Nikol has mentioned. I also noticed after treatment that my finger nails seem to split easily and my toenails were almost off. I guess that's from chemo as well.
I am interested to know how many women dx with bc were under a great amount of stress prior to dx. I partly blame that for mine. I also think that starting my period at a very young age had something to do with it too. I was only 9. Anyone else that young?
Marreb
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Adrea
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Posted: Jan 01 2008 at 4:09pm |
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Hi Nikol and Marreb
So glad to hear from you. I have always had difficulty with blood draws and had trouble for the first treatment. Have been told how hard "E" is on veins so have opted for a port. I know that there are pros and cons of the port, but have decided it is best for me. Did either of you get a port? If not, why not?
Thanks,
Adrea
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Adrea
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Posted: Jan 01 2008 at 4:12pm |
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Adrea again - forgot to mention that "YES" I was under a lot of stress prior to diagnosis. I retired in June so thought my stress was OVER!!!!
Much reported about the immune system and its ability to prevent. Stress really has adverse effect on immune system. Who knows?
Adrea
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theshalhoubs
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Posted: Jan 01 2008 at 11:19pm |
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I had a very stressful job as an ER RN. I am 37 y/o, and I was dx Jun 26th with Left Breast Triple Negative IDC 3.2 cm with 2 Axilla Lymph Nodes involved, Stage II Grade III. I started dense dose Chemotherapy 4 A / C and 4 Taxol on Jul 6th, and I had a Bilateral Mastectomy Nov 12th. I had a 100% chemotherapy affect in the lymph nodes, but I still had a 2 cm area in the removed breast tissue with 1 mm and 2 mm spots of virulent cancer cells. So, I returned to chemo on Dec 19th for 6 rounds of Abraxane. I am very interested in FEC...I just read about it tonight! I am meeting with a second Radiologist to discuss the pros and cons of Radiation...I want to live, but I cringe at thinking about getting Radiation. I really wanted reconstruction with implants, and Radiation destroys the elasticity of the skin, tissue and muscle causing a high failure rate in getting my long awaited Boob Job.
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theshalhoubs
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Posted: Jan 01 2008 at 11:20pm |
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I opted for a port b/c I did not want to ruin my veins...I am only 37 y/o...I need my veins...I hope to have many years ahead of me.
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Nikol
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Posted: Jan 02 2008 at 11:36am |
Hi Adrea, marreb and theshalhoubs
How are you? A port is a good decision for FEC. I didnīt got any port and nobody offered me this possibility at our hospital. Nowdays the nurses have problems to take me the blood. They can use only my wrists which is more painful. Using a port we could avoid the problems with veins.
As marreb has mentioned the stress prior to dx it was the same in my case.
Nikol 
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Terri
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Posted: Jan 03 2008 at 4:58am |
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Hi Adrea, I am about to have my 4th treatment of 6 FEC (every 3 weeks). I was dx aug 17 with stage 1, node negative grade 2. It makes me very nautious for about 5 days (even with meds), constipation, heartburn, and my eyes burn and tear up. My Dr prescribed stool softener that I take every day. I have a port which I didn`t like at first but now I`m very thankful for since I have to get a CBC every week and they use the port. You talk about stress before DX. I had alot of stress for 3 years before my DX, including planning my wedding 10 months before DX. I really think stress has something to do with suppressing imune system and getting cancer.
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theshalhoubs
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Posted: Jan 03 2008 at 7:43am |
Hello Terri, Nikol, and Adrea,
I personally requested a Port A Cath, I worked in the ER and I knew I didn't want someone poking me over and over for labs and meds. I figured I would save my veins for the rest of my life. I had good veins, and I told my doctor that I wanted to keep it that way.
I am going to chemo today for tx #3 of Abraxane; I will skip next week and then start the next 3 rounds on Jan 17th. Abraxane causes constipation, heartburn, mild joint pain, some chemo brain and minimal tiredness...otherwise I feel like myself b/c I take Benefiber 3xday to prevent constipation, Nexium for heartburn, Motrin (& Decadron at Chemo) for Joint Pain, and Glutamine to prevent Neuropathy (& Aloxy at Chemo for Nausea). The medications are controlling my side effects. I am going to ask my Medical Oncologist today about FEC. I was wondering if I could do FEC chemo instead of Radiation. Did any of you get Radiation? I have a second opinion appt tomorrow with another Radiology Oncologist to discuss the pros and cons of tx with Radiation. I have a lot of concerns regarding the permanent side effects of Radiation. I really don't want it, but I will do it if it is the best next step. It disappoints me, b/c it really impacts my ability to get reconstruction following my Bilateral Mastectomy.
Sincerely,
Belinda Shalhoub
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Nikol
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Posted: Jan 03 2008 at 10:49am |
Hello girls,
I got also radiation. After it I had a little red skin which is a common reaction on radiotherapy. Then the treatment was followed by Taxotere. Taxotere caused in my case skin sensitivity and together with previous radiotherapy the result was that my part of chest (treated with radiation) was very red. I was treated by a dermatologist and this problem disappeared. So also a strong unexpected skin reaction is curable. For me was chemo more hard than the radiology because this is the whole body treatment. The radiology is a local treatment, during this time I could do more things than during chemo.
Theshalhoubs you have fear of skin problems after radiology and the possible impact on your future reconstruction. The skin after radiology is really more dry and is necessary to protect it with a cream. When I use it regularly it is not so terrible. Radiology can be also an important part in breast cancer treatment. I would recommend you after talking to your doctor to think about your benefit from the whole treatment for your future. If you get radiation maybe you could consult a dermatologist what would be the best for your skin.
I wish you a good decision!
Nikol
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theshalhoubs
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Posted: Jan 03 2008 at 2:22pm |
Nikol,
Did you have reconstruction after radiation, or was this not an issue for you? I am trying to be level headed, and I want to get well...honestly that is my focus even though it has taken me a while to get to that frame of mind...putting my health before my boobs. I have read...that not only the skin, but the muscle too gets fibrosis, losing its elasticity and wont stretch over the implants after radiation therapy.
I also get concerned about the long term side effects from Radiation, esp. Lung Cancer...showing up 10 yrs later...that makes me nervous. My Med Onc said that Lung Cancer is a small risk...only about 1%. But it was a small risk to get breast cancer at 37 y/o too. Do you know that only 5 - 8 % of women with breast cancer are under the age of 40 and only 12% get TNBC, and I've seemed to manage to fall into those odds. And I know that we, as individuals, are not a statistic, but the risks are real. I am doing my best to make the best life saving decisions, and I'm trying to deal with my want for boobs. If I can get both, that would be the ultimate reward for going thru all of this.
I haven't been educated on the odds of no recurrence of TNBC with or w/out Radiation...did they tell you?
Did your pect muscles stiffen or don't you know...I am curious?
Belinda
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cepora
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Posted: Jan 04 2008 at 12:45am |
Hi all. I was diagnosed august of 06 with 2.5 cm IDC triple negative stage IIB. I had a port and have never regretted it. I had six FEC, 12 weekly taxol and 35 radiation. I had a lumpectomy and SNB with one positive node. FEC made me very constipated, fuzzy brain, exhausted. Taxol gave me bone and joint pain. Out of the two chemos, I would say Taxol kicked my butt more than the FEC did. With both chemos, the side effects got worse at time went along. Radiation is something I regret. I wish I would have had mastectomy. My skin is tough feeling, like leather almost. When I raise my arm above my head, it hurts. When I lay on my stomach sleeping, my boob hurts. Belinda...my muscles are stiffened. And stress?? Hah! Stress is my middle name!!! I am finished with all treatment as of May 2007. I am back to work full time, I go to the gym five days a week (to try to lose the 40, yes I said 40!) pounds I gained during the past year. I feel better, almost "normal" again. I do go for scans every six months and have a mammo once a year. Good luck to all of you! You can do this...if I did it anyone can!!!!!!! take care of yourselves.
joyce
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marreb
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Posted: Jan 04 2008 at 8:33am |
Hi Adrea,
I wasn't given the option of a port when I received chemo. My veins are really hard and painful. I dropped into the chemo unit today and spoke with one of the nurses. She told me that the pain should go away within a year but the hardness will never leave because of the damage from ''e''. I guess that means any blood work now will be painful too. Oh well..... it could be worse.
Marreb
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theshalhoubs
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Posted: Jan 04 2008 at 10:33am |
Joyce,
That is disappointing to hear about your muscle stiffness...I have a Physical Therapist friend who told me that he has tx pts for that exact problem...that is another reason that concerns me. Of course none of us want the chance of recurrence, so I had a bilateral mastectomy...I am going to ask the Radiology Oncologist today what are the odds with adding radiation...is it worth it.
Belinda
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Nikol
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Posted: Jan 04 2008 at 12:54pm |
Hi girls
I donīt have reconstruction. First I wanted to have it quickly after my treatment. But next year I needed another surgery and got tired of it. So I decided to wait with it but I am interested in it. I belong to the same age group as theshalhoub and know about the 5 % of women who get BC under the age of 40 (from the Young Survival Coalition).
For theshalhoub I would like to say:
I understand your desire for the best effect from reconstruction and know that it can have even an impact on survival and quality of our life. The reason why I wrote you to think about the whole benefit from the treatment was because we have TNBC. The oncs have for us only chemo and cannot give us after standard treatment Herceptin or Tamoxifen. You know I had a higher stage of BC so I accepted radiology though I have permanent side effects from it. If you wish I can ask about it more at our hospital (but I go there later). My muscles were also stiffen. I had to do a lot of training with my arm and should repeat it. It is also good for extending the skin. I wish you a nice result from the reconstruction and the best possible effect from your treatment and of course for all girls here. 
For marreb: If it is possible could you please ask for a port? FEC can injury the veins and it is very painful.
Have a nice day.
Nikol
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theshalhoubs
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Posted: Jan 04 2008 at 7:04pm |
Hi Nikol,
I just met with the Rad Onc, and we decided to do Radiation with the possibility of doing expanders first ... that depends on my Plastic Surgeon agreeing to do implants after the Rad Tx. If my P.S. wont help me, then I am going to have my Surg Onc refer me to another P.S. that will accommodate me. That's my goal for now, but I understand things tend to change along the way.
I agree on the Port...they are very valuable in saving your veins...this isn't the only time in your life that you will need your veins. I believe you should do everything to save your access...GOD forbid you ever have a cardiac arrest or traumatic car accident and the paramedics can't get venous access to save your life b/c chemo destroyed them. That is my point of view, b/c I work in an ER as an RN.
I enjoy hearing your comments and concerns. Keep it going and I pray we all have the best outcome...knowing we are all dealing with TNBC.
Belinda 
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Terri
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Posted: Jan 05 2008 at 3:54am |
Hi Belinda,
After my 6 treatments of FEC I am going to have 7 1/2 weeks of radiation. My Rad onc said it will give me a 95% chance of the bc not coming back in that area. He made it seem that the side effects were mild. After reading some of the posts I think I will ask him more about side effects but I will do the radiation no matter what b/c that and the chemo are all we have as TNBC`s.
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sftfemme
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Posted: Jan 05 2008 at 5:06pm |
I have a question about radiation after treatment.....I had a mastectomy lft side. They got great margins. I also had 3/20 nodes positive. I will have tx start this week 4 A/C every 2 weeks then 4 taxol every 2 weeks. I asked if I should have radiation but onc said no because he doesn't think it would be necessary. I was thinking under my arm and subclavical area would be beneficial. I'm going to see a rad dr about it but did any of you that had rad after a mastectomy have positive nodes?
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theshalhoubs
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Posted: Jan 05 2008 at 7:19pm |
I am having Radiation after have a discussion regarding the tx with two different Radiology Oncologist. ]
After a 1hr and 40min conversation, I learned a lot about Radiation. The Rad Onc said the hard and fast rules for Radiation tx is based on your original PETSCAN / MRI which indicated how many involved lymph nodes and size of the tumor prior to tx...another words how far your disease had progressed before you noticed it.
If your tumor was 4cm or greater or if you had 4 or more lymph nodes involved, then you get Chemo, Surgery and Radiation. The biggest problem is that the PETSCAN only picks up cancer cells 6mm or larger, and Cancer Cells can be smaller than 1mm. Therefore, if you had 2 lymph nodes illuminate on a PETSCAN, there is a great chance that you had more than 2 lymph nodes with cancer. And since they use tumor size & lymph node involvment to guide the necessecity for Radiation, if you have 2 or 3 lymph nodes involved it is wise to choose Radiation. But no one will ever know, b/c the cancer cells are to small to detect with imaging. If you had a mastectomy before Chemo, then Pathology would tell you exactly how many original lymph nodes were involved. I happen to have NeoAdjuvant Tx with Chemo then Surgery then pathology on what was left after Chemo.
I personally had 2 out of 8 nodes damaged by cancer but with a 100% chemotherapy effect according to pathology after a Bilateral Mastectomy (Left had cancer, Right was prophalactic). I am going to have Radiation 5 days a week for 7 weeks ... possibly after my expanders are in place in preparation for Reconstruction. But b/c I had Chemo first, the Radiologist said that it is possible that I had more involved lymph nodes...however at the mastectomy they looked clear. Unfortunately in my case, no one will ever know. That is one advantage to having a mastectomy first. The advantage to Chemo first is to know which chemo works best on your tumor, so they know where to concentrate their efforts with the chemo drugs. For example, A/C did not effect my tumor and Taxol did, so after my mastectomy ... the pathology said I still had cancer, so now I am doing more Taxol (in the drug form Abraxane) this time...then Radiation.
I would really like to avoid Radiation, but it scares me not to do it. The Cons of Radiation are: Rib Fractures due to weakened bone in the irradiated area, Stiffening of the lung at the tip of the tissue hit by Rads, Stiffening of Pectoral Muscle, Tightening of Skin, minimal decreased lung capacity at the top of lungs, 1% chance of Lung Cancer, and small chance of Lymph Edema. The younger you are the better your tissue and muscle will tolerate the Rads. The Pros of Radiation are: Sterilize the field affected by the cancer including the path of the lymph nodes to prevent regeneration of active cancer cells allowing them to travel throughout the body again...any cancer in the target area will be killed.
I've decided that I was already taking the most aggressive route with a Bilateral Mastectomy, so I am going to continue on that path with Radiation so that I can hopefully never revisit having cancer again...esp TNBC. I don't feel real lucky, since the odds of getting this type of cancer were low in the first place. The Radiologist said that it is always harder to deal with the cancer the second time...as it mutates and becomes more difficult to tx.
I hope that info helped; I'm trying to share the info given to me, so you guys have insight and questions to ask your doctors...to help us all. 
Belinda
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