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gwendolen
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Topic: Didn't have 100% response to chemo Posted: Aug 12 2017 at 8:59pm |
Hi ladies,
My last round of chemo was June 7th. I did 4 ac and 12 taxol. When I had my surgery my tumor showed that I had a 70% response to chemo. My oncologist called me yesterday and thinks I should do a pill form of chemo just to be on the safe side and ithe will hopefully help with recurrence. Has anyone else done this? If so did it help? Any input is much appreciated
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gordon15
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Posted: Aug 14 2017 at 9:19pm |
My wife had about 25% tumor still not killed by chemo, which she had BEFORE surgery, it's called a partial response, not a Pathological Complete Response, (pCR) I think is the abbreviation)...I think that only happens in about 25% of patients, maybe it's 33%, anyway...
after my wife's single mastectomy, the oncologist recommended Taxol chemo, and it's been about a year and she hasn't had a recurrence
She had a large (4-5 centimeters) tumor and 4- lymph nodes involved, and the chemo she had BEFORE surgery killed the cancer in the lymph nodes (that chemo was Carboplatin-Gemzar)
Edited by gordon15 - Aug 14 2017 at 9:23pm
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wife: IDC/Lobular Stage2B 2008 lumpectomy/TAC+rads TNBC Stage 3A/w/metaplastic/squamous Nov2015 Carboplatin-Gemzar chemo/masectomy Taxolchemo+rads 4-16 PET scan stable 9-2016/ 1-2017
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gwendolen
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Posted: Aug 14 2017 at 9:40pm |
Thank you for your response gordon15. I did 12 rounds of taxol before surgery. I'm not sure what chemo pill my oncologist is going to recommend I just pray it works!
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gordon15
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Posted: Aug 15 2017 at 9:10am |
It might be Xeloda (Capecitabine) you can use the "search" at top right of page to see posts regarding it.
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wife: IDC/Lobular Stage2B 2008 lumpectomy/TAC+rads TNBC Stage 3A/w/metaplastic/squamous Nov2015 Carboplatin-Gemzar chemo/masectomy Taxolchemo+rads 4-16 PET scan stable 9-2016/ 1-2017
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Alive2day
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Posted: Sep 17 2017 at 8:40pm |
I could have written that post. same chemo. same results. before surgery. Last chemo was 6/30. Surgery last week. Haven't seen oncologist yet. However, prior to surgery, she discussion the option of having to take an oral chemo for the remainder of my life.
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123Donna
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Posted: Sep 18 2017 at 7:55am |
Please read this thread about Xeloda for situations where a pCR wasn't achieved.
Xeloda improves survival for some breast cancer patients who do not achieve a pathological complete response to chemotherapy A drug called Xeloda can extend the lives of some women whose breast cancer is not wiped out by standard treatment, a new clinical trial finds. Oncologists said the results are "practice-changing."
Donna
Edited by 123Donna - Sep 18 2017 at 7:55am
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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09) 11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
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Tenley
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Posted: Nov 12 2017 at 9:20pm |
Good evening,
I am going to pretty much pose the same question, but with a slightly different spin...
Has anyone's Oncologist given you the option to 1) do nothing after neoadjuvant chemo and surgery based on path reports (only 3mm of cancer remaining, went from Stage 2b to Stage 1a, no lymph nodes, clear margins), 2) take Xeloda x 6 months, 3) enroll in a clinical trial: placebo vs. PARP inhibitor (for those w/ BRCA 1 mutation)? My husband and I are at a crossroads....what did you do if/when given these options?
Thank you,
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123Donna
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Posted: Nov 13 2017 at 7:32am |
Hi Tenley,
You might want to consider getting a second opinion. I found it could help when making a decision on how to proceed in your treatment plan. Were you tested for the BRCA gene?
There was another thread talking about Xeloda for those who didn't achieve a complete pcr. The information might be helpful to you in making your decision.
Donna
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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09) 11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
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Tenley
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Posted: Nov 13 2017 at 6:54pm |
Hello there,
Yes, I was tested and am BRCA1 positive. I am really leaning towards getting a second opinion. Hopefully, it will be helpful and not overwhelm me more!
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123Donna
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Posted: Nov 14 2017 at 8:09am |
Tenley,
When I had my recurrence, I got a second opinion from another top doc at an NCCN cancer facility. He supported the clinical trial my onc wanted me to try, but also told me about a couple of other options. I ended up getting three opinions regarding radiation therapy, even traveling to MD Anderson. The two other opinions concurred with the planned treatment areas so it gave me comfort that I was making the best decision for me.
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DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09) 11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
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