Go To Main TNBC Website


  New Posts New Posts RSS Feed - Tumor shrinkage during chemo
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Tumor shrinkage during chemo

 Post Reply Post Reply Page  12>
Author
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Topic: Tumor shrinkage during chemo
    Posted: Mar 30 2013 at 7:13pm
Has anyone had chemo prior to tumor removal?  Did you notice any shrinkage and if you did at what point?  My doctor said I might see it with this first treatment.  I did see the pain go away, today I had some discomfort but it is not as bad as after my biopsy.  

Just curious other experience.

Thanks
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
weekender09 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 29 2013
Location: United States
Status: Offline
Points: 135
Post Options Post Options   Thanks (0) Thanks(0)   Quote weekender09 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 30 2013 at 11:48pm
Julie:  

I will have chemo 3 on Monday.  I noticed the pain go away by treatment 2 as before that I could have chopped my boob off myself it hurt so bad.  But I totally can tell the tumor has been shrinking as can my mom and boyfriend.  At number 2 the PA also said it appeared to be shrinking in size.  This gives me so much positive reinforcement.  One friend said My story makes her think of the Wicked Witch Melting Away.... I like that analogy. 

Here's hoping our Witches melt away!!

Barb
02/12/13 DX TNBC, Grade III, Stage 3, 3.3cm tumor, IMN and 1 lymph Positive, Chemo A/C T complete 6/13
BRCA1-/BRCA2+ Variance, BIL 7/13, 33 RADS complete 10/13 Remssion :)
Back to Top
rosered71169 View Drop Down
Groupie
Groupie
Avatar

Joined: Mar 19 2012
Location: Northern Ohio
Status: Offline
Points: 88
Post Options Post Options   Thanks (0) Thanks(0)   Quote rosered71169 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 31 2013 at 12:24am
Yes, I had neoadjuvant chemo. I had an MRI halfway through - after chemo 3 of 6 total. They could not see any tumor or lymph node involvement on the MRI scan! What a miracle that the chemo worked so well. My surgery confirmed those results. Hope your chemo works just as well!
IDC 2-21-2012 @ age 42 TNBC, Stage IIA, Gr 3, 1.5cm Tumor Rt Breast, 3 Lymph Nodes, Neoadj Chemo, TACx6,BRCA Neg, Bilateral Mastectomy 7-30-12, 28 Rads, Bilateral DIEP 5-22-13...3 Beautiful Daughters
Back to Top
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 31 2013 at 9:06am
I like that analogy too!  I guess I started to worry.  I know the pain went away right away and I should be happy with that happening after one treatment.  Yesterday I had a very dull ache and this is probably what started the worry.  The what if's started in my head.  My next appointment is Tuesday and I am ready to hit this thing with the second punch.  A family member who went through ovarian cancer gave me another good analogy for my kids.  She told me to tell them the chemo was like pacman and it was going to gobble up the cancer.  This way they know the cancer is the bad guy and not the chemo when I am weak and not feeling well.  
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
weekender09 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 29 2013
Location: United States
Status: Offline
Points: 135
Post Options Post Options   Thanks (0) Thanks(0)   Quote weekender09 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 31 2013 at 7:56pm
Love That!! Good Luck Tuesday.  My number three is tomorrow so tonight is a zanax night so I can sleep and not obsess over the ishy pacman!  
02/12/13 DX TNBC, Grade III, Stage 3, 3.3cm tumor, IMN and 1 lymph Positive, Chemo A/C T complete 6/13
BRCA1-/BRCA2+ Variance, BIL 7/13, 33 RADS complete 10/13 Remssion :)
Back to Top
sweetpickle View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 28 2012
Location: North Carolina
Status: Offline
Points: 91
Post Options Post Options   Thanks (0) Thanks(0)   Quote sweetpickle Quote  Post ReplyReply Direct Link To This Post Posted: Apr 01 2013 at 4:11pm
Hi Julie,

Im doing cemo right now and my tumor went from 4.3cm to undetectable by palpatation after four A/C chemos. I had one Taxol and one Taxotere and still cant feel anything, I have two taxotere treatments left. I will know more when I have surgery but so far it seems like it may be gone. At least thats what Im hoping for.
11/13/12 DX TNBC, BRCA 1+ Grade 3, 4.3cm tumor, susp. node under arm, 4 A/C biweekly & 4 Taxol biweekly
Back to Top
momof2 View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 07 2012
Location: California
Status: Offline
Points: 65
Post Options Post Options   Thanks (1) Thanks(1)   Quote momof2 Quote  Post ReplyReply Direct Link To This Post Posted: Apr 01 2013 at 7:49pm
LOL!!! That's what my chemo oncology doctor, nurse, and I would say about my tumor..."It's meltinggggg!!!"  instead of "I'm meltingggg!" hehehe
TNBC/ILCw/MedullaryFeatures 9/19/12/age39,Stage2b,Grade 3,4x4cm,InternalMammary 1.3x0.6cm,16 NodesRemoved/rb lumpectomy/ClearMargins 3/15/13,BRCA1/2 Neg,8x AM386/Taxol;4x A/C;34Rads6/26/13;NED5/18/16
Back to Top
momof2 View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 07 2012
Location: California
Status: Offline
Points: 65
Post Options Post Options   Thanks (0) Thanks(0)   Quote momof2 Quote  Post ReplyReply Direct Link To This Post Posted: Apr 01 2013 at 7:52pm
I was in the I Spy Clinical Trial in La Jolla, CA (UCSD/UCSF) and my tumor was shrinking but then began to grow again after the 7th treatment (receiving 1x wk)...on trial from 10/25-12/13 and 12/20 took me off and put on me on A/C (Red Devil) treatment every other week til 1/31 and tumor began shrinking after 1st treatment and became undetectable in my right breast, lymphnodes, and internal mammary..needless to say my doctors were all extremely happy and I went on to have a lumpectomy, removed 16 lymphnodes, and port removed at same time on 3/15/13; had clear margins in path report.  It's been two weeks since surgery and I'm feeling this burning/irritation in right nipple...I hope that's part of the healing process..concernedUnhappy 
TNBC/ILCw/MedullaryFeatures 9/19/12/age39,Stage2b,Grade 3,4x4cm,InternalMammary 1.3x0.6cm,16 NodesRemoved/rb lumpectomy/ClearMargins 3/15/13,BRCA1/2 Neg,8x AM386/Taxol;4x A/C;34Rads6/26/13;NED5/18/16
Back to Top
Lillie View Drop Down
Senior Member
Senior Member
Avatar

Joined: Jul 10 2009
Location: Eastern NC
Status: Offline
Points: 3586
Post Options Post Options   Thanks (0) Thanks(0)   Quote Lillie Quote  Post ReplyReply Direct Link To This Post Posted: Apr 01 2013 at 9:21pm
Praise God for all the Melting tumors in all of you young ladies.  I had surgery first, so i wasn't able to experience that, but what wonderful thought.  The Wicked Tumor To The Right and To The Left is Melllltttttiiiiinnnnggggggg.  Stay strong, all of you.
 
God Bless,
Lillie
Dx 6/06 age 65,IDC-TNBC
Stage IIb,Gr3,2cm,BRCA-
6/06 L/Mast/w/SNB,1of3 Nodes+
6/06 Axl. 9 nodes-
8/8 thru 11/15 Chemo (Clin-Trial) DD A/Cx4 -- DD taxol+gemzar x4
No Rads.
No RECON - 11/2015-9 yrs NED
Back to Top
debB View Drop Down
Senior Member
Senior Member
Avatar

Joined: Sep 14 2011
Location: Central Illinoi
Status: Offline
Points: 692
Post Options Post Options   Thanks (0) Thanks(0)   Quote debB Quote  Post ReplyReply Direct Link To This Post Posted: Apr 01 2013 at 10:04pm
Hi Julie,

I wrote a response right after you posted the other night and now it doesn't seem to be here. My ipad and I don't seem to be getting along with posting. anyway... to repeat!

I had neoadjuvant chemo nearly two years ago. I too had a painful tumor but I don't think the pain was totally gone by the second treatment. I do think the tumor was softening and definitely noticed a big difference by treatment three. Prior to chemo it was growing like the proverbial weed in the four weeks from when I found it until starting chemo, so I checked that thing all the time! I did not have any scans along the way. They talked about it initially, but when it was abviously doing the job, they felt there was no need.

Sweetpickle- hoping that tumor is totally GONE!

Fingers crossed ladies!
Deb
Dx 4/29/11, 46 yrs old, 3.9 cm tumor, Stg 2 Grade 3 chemo 4 rounds DD AC, 12 weekly taxol, finish. Lumpectomy, 2mm residual tumor. 37 rounds rads completed. Cisplatin/PARP trial
Back to Top
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Posted: Apr 03 2013 at 5:54am
Thanks ladies.  I saw my dr yesterday before my second treatment.  She said the pain diminishing was a good first step.  I told her I thought i might have gone down at first but now I wasn't so sure.  She said its "the same size but I do agree it feels different, more moveable".  She also told me there can be scar tissue that has formed so they will only know if it pathogen free until the surgery is done and they examine the tissue.  She said sometimes it can feel like something is still there but all that you are feeling is scar tissue.  I love my doctor she always has the right things to say to make me feel better.  
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Posted: Apr 03 2013 at 5:57am
Your analogy is funny because I always say on my way to chemo "off to see the wizard" and I get the wizard of oz song stuck in my head, "Because of the wonderful things he does!"  I made this up for my kids but I like it more i think!  :)
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
momof2 View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 07 2012
Location: California
Status: Offline
Points: 65
Post Options Post Options   Thanks (0) Thanks(0)   Quote momof2 Quote  Post ReplyReply Direct Link To This Post Posted: Apr 03 2013 at 10:16am
Julie,
Too cute and hilarious...we have to keep our humor!!  I tend to watch tons of comedy and would take comedy dvds with me to my chemo infusion center.  I would be the only one cracking up and all the nurses would always come by to take a peek at what was so hilarious.  Positive attitude plus keeping your mind off of what is happening was my spin on it all.  Go to You Tube and watch Chonda Pierce...clean humor and hilarious!!!!  I also bought her cds for car ride over...center is between 2-3hrs away depending on traffic.  My little one (kinder) does magic tricks for me and tries to make me laugh as much as possible/well I do it for him as well...keeping it as "normal" as possible for everyone!Smile
TNBC/ILCw/MedullaryFeatures 9/19/12/age39,Stage2b,Grade 3,4x4cm,InternalMammary 1.3x0.6cm,16 NodesRemoved/rb lumpectomy/ClearMargins 3/15/13,BRCA1/2 Neg,8x AM386/Taxol;4x A/C;34Rads6/26/13;NED5/18/16
Back to Top
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Posted: May 01 2013 at 2:30am
I have good news to report.  I had my last AC treatment today.  Also my tumor has shrunk enormously.  It is very deep and hard to feel the margins.  Still something is there width wise, which makes me nervous.  So many say they feel nothing after 4 AC treatments, and while I have had a good response, something is definitely still there.  I am hoping Taxol continues the shrinking trend.  Oh what a worrier I have become.  :)  

Thanks again ladies.

- Julie 
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
MarissaK View Drop Down
Groupie
Groupie
Avatar

Joined: Jan 06 2013
Location: Northern Cali
Status: Offline
Points: 84
Post Options Post Options   Thanks (0) Thanks(0)   Quote MarissaK Quote  Post ReplyReply Direct Link To This Post Posted: May 01 2013 at 12:35pm
Julie, sounds like you are moving along great and with positive progression on the AC. It is a very good sign that the texture of your tumor feels to be changing or breaking down, even if you still feel something there at this point. My docs told me the same thing about the scar tissue and they were right. My tumor melted away relatively quick after starting A/C, but I was still paranoid feeling a little something under my arm the entire time (I had lymph node involvement). My doctor kept telling me she thought it was scar tissue from the tumor breaking down. Anyhow, at time of surgery my path revealed a pCR with nothing left but fibrous tissue in the breast and "fibrous scarring" in the axilla. 

Hope you do just as well on the Taxol.

Take care.
DX 5/18/12 at age 34. Stage IIIC IDC TNBC, grade 3, 3 cm (multiregional nodal involvement). DD ACT complete 9/5/12. BMX 10/15/12, ALND: 0/12 nodes. pCR. Rads x 25 + 3 boosts completed 2/6/13. BRCA neg
Back to Top
TriplePositiveGirl View Drop Down
Senior Member
Senior Member


Joined: Oct 07 2010
Location: Los Angeles, CA
Status: Offline
Points: 665
Post Options Post Options   Thanks (0) Thanks(0)   Quote TriplePositiveGirl Quote  Post ReplyReply Direct Link To This Post Posted: May 01 2013 at 12:52pm
That is great Julie! Try not to worry - sounds like the chemo is doing its job!

Best Wishes for continued success,
Lisa
Diagnosed Jan 2010; Stage IIa, grade 2, 3.2cm in rt. breast, no nodes and BRCA-. 4 cycles Carbo/Gemzar 3/10; Lump 6/10; 2 cycles carbo/gem after surgery 8/10; 35 Rads finished 12/1/10. NED.
Back to Top
sweetpickle View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 28 2012
Location: North Carolina
Status: Offline
Points: 91
Post Options Post Options   Thanks (0) Thanks(0)   Quote sweetpickle Quote  Post ReplyReply Direct Link To This Post Posted: May 01 2013 at 3:09pm
Congrats Julie! Sending lots of melting vibes your way :-)    I just completed chemo and it looks like mine is still gone, on to surgery May 24th.   Keep going and try to laugh as much as you can, I think that helps a ton!
11/13/12 DX TNBC, BRCA 1+ Grade 3, 4.3cm tumor, susp. node under arm, 4 A/C biweekly & 4 Taxol biweekly
Back to Top
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Posted: May 01 2013 at 8:57pm
Did you ladies have any tests mid or end of chemo to look at the tumor size?  
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
MarissaK View Drop Down
Groupie
Groupie
Avatar

Joined: Jan 06 2013
Location: Northern Cali
Status: Offline
Points: 84
Post Options Post Options   Thanks (0) Thanks(0)   Quote MarissaK Quote  Post ReplyReply Direct Link To This Post Posted: May 02 2013 at 2:17am
I did not during chemo. I inquired, but my oncologist and surgeon said it wasn't necessary because they could tell by palpating that the mass was clearly disappearing, which meant the chemo was working. A month after I finished chemo, and one week before my surgery, I had an updated PET/CT, which confirmed NED but showed a tiny something still left in the breast/axilla. This turned out to be scar tissue.

DX 5/18/12 at age 34. Stage IIIC IDC TNBC, grade 3, 3 cm (multiregional nodal involvement). DD ACT complete 9/5/12. BMX 10/15/12, ALND: 0/12 nodes. pCR. Rads x 25 + 3 boosts completed 2/6/13. BRCA neg
Back to Top
JulieKCA2013 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 12 2013
Location: United States
Status: Offline
Points: 217
Post Options Post Options   Thanks (0) Thanks(0)   Quote JulieKCA2013 Quote  Post ReplyReply Direct Link To This Post Posted: May 02 2013 at 4:41am
Thanks Marissa, I definitely do feel better, whatever is left is very deep, it also makes me feel better about not finding it until it was 4cm.  It is very hard to distinguish between the other normal fibrous tissue since I have dense breasts.  The nurse practitioner asked at my last visit if I felt anything else and I pointed out a spot on my right breast that I had noticed a few bumps.  She told me no that is just over lapping breast tissue.  How am I suppose to distinguish that? Main reason I am doing bilateral removal after chemo.  :) 
Dx 3-7-13 TNBC, 5cm pT2N1M0
3-19-13 ACx4, 5-14-13 Taxolx4
7-17-13 BMX ypT1N2M0(.9mm) 4/24 nodes.
10-8-13 completed Rads x 30
12-3-13 completed Eribulin Trial
10-18-13, 3-19-14 Bone/Ct Scan Clear
Back to Top
 Post Reply Post Reply Page  12>
  Share Topic   

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 11.05
Copyright ©2001-2016 Web Wiz Ltd.