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SRC Inhibitors

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trip2 View Drop Down
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    Posted: Jul 13 2007 at 4:24am
http://www.eurekalert.org/pub_releases/2007-07/joci-sim070307.php
 
 
This is hard to read but it is hope.
 
"The data raise the possibility that for at least a subset of ER-alpha–negative breast cancers, Src may stimulate estrogen-dependent ER-alpha degradation, resulting in a lack of ER-alpha detection, and more aggressive tumor growth. The authors conclude that their study provides a rationale for the use of Src inhibitors in breast cancer therapy."
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MarilyninMiami View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote MarilyninMiami Quote  Post ReplyReply Direct Link To This Post Posted: Jul 13 2007 at 11:53am
Pam,
This is great...dont know if it has an practical implications for us yet, but have written to Dr Slingerland, who is right here in Miami.
Will post her reply.
thanks for finding! Marilyn
MARILYN from Miami
dx:6-05, trip neg, basoloid, gr 3, stage IIB, lumpectomy,SNB w total axillary node surg 3pos/34 dose dense ACT, 33 rads, BMB (neutropenia) NED!!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote CalGal Quote  Post ReplyReply Direct Link To This Post Posted: Jul 13 2007 at 4:12pm
Thanks Pam!  Very interesting. 

Marilyn, great that you wrote to Dr. Slingerland.  I'm interested to hear what she has to say.

CalGal
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trip2 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote trip2 Quote  Post ReplyReply Direct Link To This Post Posted: Jul 14 2007 at 6:29am
Look forward to hearing from you Marilyn, good luck!
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