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new treatment for mets

Printed From: TNBC Foundation
Category: TNBC Forums
Forum Name: TNBC Talk
Forum Description: A place to chat
Printed Date: May 24 2018 at 4:11am
Software Version: Web Wiz Forums 11.05 -

Topic: new treatment for mets
Posted By: HrseLvr62
Subject: new treatment for mets
Date Posted: Feb 12 2017 at 7:57pm
I have tnbc w/mets to lungs & bones. After approximately 1 year on Xeloda, my doctor has started me on the male hormone drug - First Xtandi & now Bicalutamide. Ask your doctors if your tumors are androgen receptors.. Mine are. The results have been dramatic - I am almost cancer free after only a few months. Just wanted to share, as this is a very new approach to metastatic tnbc. There are a lot of clinical trials going on wit these drugs.

Posted By: mainsailset
Date Posted: Feb 13 2017 at 9:15am
That is such wonderful news to hear about the success of your treatment. Thank you to your doctor for giving you the treatment and thank you to you for sharing. It's not an overstatement that here at the Tneg Foundation information saves lives!!!

dx 7/08 TN 14x6.5x5.5 cm tumor

3 Lymph nodes involved, Taxol/Sunitab+AC, 5/09 dbl masectomy, path 2mm tumor removed, lymphs all clear, RAD 32 finished 9/11/09. 9/28 CT clear 10/18/10 CT clear

Posted By: GrammaSue
Date Posted: Feb 13 2017 at 6:58pm
Great news and thank you for sharing this! 

Posted By: Tulips
Date Posted: Feb 13 2017 at 10:43pm
That's wonderful!  I have heard some doctors say that we may need to start calling it Quadruple Negative, because targeting the androgen receptor for those who are positive is very effective, so soon they should be checking everyone for ER, PR, HER2, and AR.  I am glad you are lucky to have the androgen receptors, and I hope this treatment works for you for a very very long time!

Dx April 2015 IDC TN 2.2 cm, Grade 3, Chemo started May 2015: Taxol/Carbo then AC, Lx with SNB Nov 2015, 33 Rad Dec 2015-Feb 2016. 6 months Capecitabine starting March 2016

Posted By: 123Donna
Date Posted: Feb 14 2017 at 10:33pm
Kudos to your medical team!  More TNBC patients may benefit from additional testing for the AR too.


DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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