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Veliparib Study For Brca 1 or 2 Metastatic BC

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Topic: Veliparib Study For Brca 1 or 2 Metastatic BC
Posted By: trip2
Subject: Veliparib Study For Brca 1 or 2 Metastatic BC
Date Posted: Dec 16 2012 at 1:52pm
http://www.facingourrisk.org/information_research/NCT01506609.php - http://www.facingourrisk.org/information_research/NCT01506609.php
Criteria
 

Study identifier: NCT01506609
http://www.clinicaltrials.gov/ct2/show/study/NCT01506609?term=ABT-888&show_locs=Y -

  • or Her2neu positive and have received previous anti-Her2neu therapy or are ineligible for anti-Her2neu therapy
  • Subjects must have measurable disease
  • Exlusion Criteria

    • Patients must be at least 21 days out from prior chemotherapy, radiation therapy, or investigational agent
    • May not have received more than 1 prior line of cytotoxic chemotherapy
    • May not have received prior therapy with with temozolomide, a platinum agent, or a PARP inhibitor
    • May not have received prior taxane therapy for metastatic disease
    • May not have a history of brain or leptomeningeal metastasis
    • See clinicaltrials.gov website or contact study team for other exclusion criteria


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    Stage 2 2003
    Stage 1 2007
    BRCA 1+



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