Go To Main TNBC Website


  New Posts New Posts RSS Feed - Pathological Complete Response?
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

Pathological Complete Response?

 Post Reply Post Reply
Author
sweetpickle View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 28 2012
Location: North Carolina
Status: Offline
Points: 91
Post Options Post Options   Thanks (1) Thanks(1)   Quote sweetpickle Quote  Post ReplyReply Direct Link To This Post Topic: Pathological Complete Response?
    Posted: Jan 30 2013 at 6:09pm
I'm curious how many people had a PCR their first time around with chemo?  My tumor measured 4.3cm before starting A/C and it's down to about 2cm after two A/C treatments.  Do they tend to continue to shrink if they are showing a good response to the chemo?  Is this a good indicator for the future?

Thanks!Smile
11/13/12 DX TNBC, BRCA 1+ Grade 3, 4.3cm tumor, susp. node under arm, 4 A/C biweekly & 4 Taxol biweekly
Back to Top
rosered71169 View Drop Down
Groupie
Groupie
Avatar

Joined: Mar 19 2012
Location: Northern Ohio
Status: Offline
Points: 88
Post Options Post Options   Thanks (0) Thanks(0)   Quote rosered71169 Quote  Post ReplyReply Direct Link To This Post Posted: Jan 30 2013 at 7:41pm
I did have a PCR after chemotherapy treatment. I had six TAC treatments followed by a bilateral mastectomy. Originally I had a 1.5 cm tumor and two positive nodes. I did have an MRI halfway through my treatments and they saw no tumors! When the tissue was removed and tested there were no cancerous cells found.
 
Chemotherapy for TNBC can be very rough on your whole body including those nasty cancer cells. If your tumor is shrinking I would think that is a very good sign. Think positive thoughts and I will keep you in my prayers!


Edited by rosered71169 - Jan 30 2013 at 7:43pm
IDC 2-21-2012 @ age 42 TNBC, Stage IIA, Gr 3, 1.5cm Tumor Rt Breast, 3 Lymph Nodes, Neoadj Chemo, TACx6,BRCA Neg, Bilateral Mastectomy 7-30-12, 28 Rads, Bilateral DIEP 5-22-13...3 Beautiful Daughters
Back to Top
debB View Drop Down
Senior Member
Senior Member
Avatar

Joined: Sep 14 2011
Location: Central Illinoi
Status: Offline
Points: 692
Post Options Post Options   Thanks (0) Thanks(0)   Quote debB Quote  Post ReplyReply Direct Link To This Post Posted: Jan 30 2013 at 7:54pm
Hi Sweetpickle,

My tumor was probably about the size of yours when I started chemo. I did the standard 4AC and 12 Taxol. All the work-up before surgery showed no tumor, but the final path showed 2mm residual disease. It also showed some cells had made it to a node but chemo knocked them out.

I believe the stats for TN are in the neighborhood of 30% achieve a pCR, which has a much better prognosis. If I remember correctly, I also seem to recall that BRCA+ women have a higher pCR rate. Sounds like a good indicator that chemo is doing it's job! Go get 'em girl!!

Deb
Dx 4/29/11, 46 yrs old, 3.9 cm tumor, Stg 2 Grade 3 chemo 4 rounds DD AC, 12 weekly taxol, finish. Lumpectomy, 2mm residual tumor. 37 rounds rads completed. Cisplatin/PARP trial
Back to Top
sweetpickle View Drop Down
Groupie
Groupie
Avatar

Joined: Nov 28 2012
Location: North Carolina
Status: Offline
Points: 91
Post Options Post Options   Thanks (0) Thanks(0)   Quote sweetpickle Quote  Post ReplyReply Direct Link To This Post Posted: Jan 30 2013 at 8:38pm
Thanks guys! Hoping for even more shrikage with round three a/c this week!
11/13/12 DX TNBC, BRCA 1+ Grade 3, 4.3cm tumor, susp. node under arm, 4 A/C biweekly & 4 Taxol biweekly
Back to Top
 Post Reply Post Reply
  Share Topic   

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 11.05
Copyright ©2001-2016 Web Wiz Ltd.