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Parp Inhibitor

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lili03 View Drop Down
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    Posted: May 08 2015 at 6:20pm
Has anyone here participated in a clinical trial with a parp inhibitor? I am Stage 3A and have had one chemo. Can you start a Parp inhibitor after you have started chemo?
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Lillie View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Lillie Quote  Post ReplyReply Direct Link To This Post Posted: May 08 2015 at 8:10pm
Hello lili03,
I am sorry I cannot answer your question about parp inhibitor, but there are others here who can. I want to welcome you to the TNBC site. I am sorry you are having to seek information about cancer. What chemo regimen are you on? Have you had any surgery yet? Keep posting and let us know how you are. WE UNDERSTAND...

God Bless,
Lillie
Dx 6/06 age 65,IDC-TNBC
Stage IIb,Gr3,2cm,BRCA-
6/06 L/Mast/w/SNB,1of3 Nodes+
6/06 Axl. 9 nodes-
8/8 thru 11/15 Chemo (Clin-Trial) DD A/Cx4 -- DD taxol+gemzar x4
No Rads.
No RECON - 11/2015-9 yrs NED
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lili03 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote lili03 Quote  Post ReplyReply Direct Link To This Post Posted: May 10 2015 at 9:44pm
Thank you for your reply. I have had one Chemo and due for another one this Thursday. I am doing the AC dose dense for 4 times and then I go to 12 of the Taxol. Really dreading the whole hair falling out thing. 
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123Donna View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: May 10 2015 at 11:02pm
lili03,

I participated in a trial for a parp inhibitor. Many times with clinical trials they have criteria to participate.  There is usually a waiting period if you've been on a previous chemo regimen.  Are you BRCA positive?  

Here's a link to clinical studies involving parp inhibitors.

DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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