Go To Main TNBC Website


  New Posts New Posts RSS Feed - New diagnosis, need opinions
  FAQ FAQ  Forum Search   Events   Register Register  Login Login

New diagnosis, need opinions

 Post Reply Post Reply Page  12>
Author
lawana901 View Drop Down
Newbie
Newbie


Joined: Feb 29 2012
Status: Offline
Points: 3
Post Options Post Options   Thanks (0) Thanks(0)   Quote lawana901 Quote  Post ReplyReply Direct Link To This Post Topic: New diagnosis, need opinions
    Posted: Feb 29 2012 at 10:10pm
I'm a fairly new diagnosis.  My story is kind of odd.  I had went with my mom for genetic testing when the counselor suggested I be tested.  After arguing with insurance for a couple months, my testing was finally approved.  I tested positive for BRCA1 mutations.  After deciding to have prophylactic mastectomy, I went for stardand recommended scans.   They found a mass on MRI and ultrasound.  Biopsy positive for TN IDC 1.9cm.  I decided to go with neo-adjuvant chemo 6 rounds Taxotere/Adriamycin/Cytoxan.  I will have bilateral mastectomy following surgery.  My sentinel node biopsy was negative.  A few spots on my liver, but doctors thinking they are cysts.  So hoping they are correct.  Basically I am asking for any suggestions of anything above and beyond standard treatment.  I'm 31 and have a 16 months old.   Really trying to stay positive although being dealt this really crummy diagnosis.  I have researched a clinical trial that involves Cisplatin and parp inhibitor if I don't have complete response from neo-adjuvant chemo.   Is anyone familiar with this study or anything else I can do to see me through several more years.  I've really gotta see my baby grow up. 
Back to Top
123Donna View Drop Down
Senior Member
Senior Member
Avatar

Joined: Aug 24 2009
Location: St. Louis, MO
Status: Offline
Points: 12733
Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Feb 29 2012 at 10:26pm
I'm so sorry you found out your are BRCA1 positive, but the screening might have been a good thing as it caught your cancer.  You sound like you have done some research and already looking at clinical trials if you don't have a complete pathological response (cPR).  There are several women that are in the clinical trial with Cisplatin.  Hopefully they'll see your thread and comment on their experience.   Here's the trial:


Stay strong.  We are here for you.  I know this diagnosis really sucks, but you can fight it.  

Donna


DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

Back to Top
rigatonismom View Drop Down
Senior Member
Senior Member
Avatar

Joined: Sep 22 2010
Location: Albuquerque, NM
Status: Offline
Points: 264
Post Options Post Options   Thanks (0) Thanks(0)   Quote rigatonismom Quote  Post ReplyReply Direct Link To This Post Posted: Feb 29 2012 at 11:40pm
Hi Lawana,
I am on the clinical trial you are looking at.  I have done the Cisplatin and 15 of the 24 PARP treatments after the Cisplatin.  I'm not sure what to tell you about it.  To me the Cisplatin was not as hard as A/C but it took my blood counts lower.  I didn't fell as phyically bad but I was pretty exhausted.  The PARP is a piece of cake.  It is probably a good sign that they have developed a pill call rucaparib for the PARP.  It is so much easier to take the pills once a week instead of going for an infusion.  The clinical trial is a phase II so I presume since they created the pill they are going to take it to a phase III.
Let me know what other questions I can answer for you.
Nita
DX 09/10 TNBC Stage3c, grade3, Tumor 2.7cm, chemo started 9/29/10, AC x4, Taxol x12, lumpectomy 4/11/11-tumor .6cm, 3+/22 nodes, radiation x 30 finished 6/30/11.Clinical Trial Cisplatin,PARP 8/23/11
Back to Top
debB View Drop Down
Senior Member
Senior Member
Avatar

Joined: Sep 14 2011
Location: Central Illinoi
Status: Offline
Points: 692
Post Options Post Options   Thanks (0) Thanks(0)   Quote debB Quote  Post ReplyReply Direct Link To This Post Posted: Mar 01 2012 at 6:10am
Hi Lawana,

So sorry that you had to join us here, but as you have probably seen, it is a wonderful group of people.

I started this study just yesterday! I don't have anything much to tell you about it just yet though. If you pop over to the polls forum, there has been some discussion about it there also. It is being offered at quite a few centers nationally and seems to be a very good trial.

I personally think neoadjuvant is a great way to go because they can monitor tumor response. There have been a few BRCA + gals here, mindy most recently, that had tumor growth on Taxol, which is a cousin to Taxotere, so you may want to keep an eye on that. She is off preparing for surgery next week, but you may want to chat with her at some point.

I had a very good response to chemo and only had a very small tumor remaining. I had gone for a second opinion with a TNBC savvy doc and he suggested that we hit it heavy now, up front, so hopefully we won't have to deal with it later. As you probably already realize, chemo is the only thing we currently have to treat this monster.

Best of luck to you and do keep us posted with your progress.
Deb
Dx 4/29/11, 46 yrs old, 3.9 cm tumor, Stg 2 Grade 3 chemo 4 rounds DD AC, 12 weekly taxol, finish. Lumpectomy, 2mm residual tumor. 37 rounds rads completed. Cisplatin/PARP trial
Back to Top
Lee21 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Dec 22 2011
Location: Michigan
Status: Offline
Points: 736
Post Options Post Options   Thanks (0) Thanks(0)   Quote Lee21 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 01 2012 at 11:17am
Hi Lawana
Have you been over to the OPEN ACCESS thread?
http://forum.tnbcfoundation.org/open-access-links-articles-tnbc_topic9440.html
We have loads of information on different aspects of TNBC that will be useful to you as you travel down this path.
From my reading, I think platinum drugs are good for BRCA1 mutation carriers as are probably PARP inhibitors.  One caveat: if you are in the trial that Deb and Nita are in, you might not get both of the drugs.  So you might want to discuss this aspect with your oncologist.  In the OPEN ACCESS thread, look for the reviews on treatment.
12/9/11 @59,IDC,grade3, TNBC,3cm(MRI),SLNB0,stage IIA, BRCA1 variant
1/30/12 DD AC-T, 6/7/12 Lumpectomy, ypT1b(0.8 cm), 7/9/12 Rads x 30
11/9/12, clinical trial cisplatin/rucaparib, cisplatin-only arm
Back to Top
turtle View Drop Down
Senior Member
Senior Member
Avatar

Joined: Feb 05 2012
Location: Durham, NC
Status: Offline
Points: 161
Post Options Post Options   Thanks (0) Thanks(0)   Quote turtle Quote  Post ReplyReply Direct Link To This Post Posted: Mar 01 2012 at 11:31am
Hi Lawana,

Just joining the other wonderful folks on this forum in welcoming you to this informative and supportive site. Best wishes in your journey, and keep us posted on your progress and decision-making process. That's been an important helpful aspect of this site for me, and I hope that you will find comfort here as well.
DX IDC TNBC 1/15/12 @ 46; MRI 2.4cm gr3 BRCA2+ 6174delT; LMX 1/31/12 2.5cm, pT2pNO(i)pMX, lymphovascular invasion present; 2/20/12 TAC X 6; 7/2/12 Rad X 25; 9/27/2012 2nd mastectomy & BSO surgery
Back to Top
BethP View Drop Down
Groupie
Groupie
Avatar

Joined: Jan 24 2012
Location: Denver
Status: Offline
Points: 48
Post Options Post Options   Thanks (0) Thanks(0)   Quote BethP Quote  Post ReplyReply Direct Link To This Post Posted: Mar 01 2012 at 4:56pm
Hi, Lawana,

I just wanted to let you know that I am on the same chemo regimen as you are: 6 rounds of TAC before surgery. So far the lymph node that swelled up last September is shrinking. I can feel it myself, so that is a hopeful sign. I don't know whether my primary tumor is shrinking, as it was only visible on MRI and nobody has been able to feel it.

I'm sorry about your diagnosis but glad it hasn't spread to the lymph nodes. That is a good thing. I hope your chemo goes well. And I hope you can find some way to relax and not think about cancer from time to time. 

If you want any information on what I've done to cope with the side effects of TAC, please let me know. 
Dx November 21, 2011: IDC, not staged; Gr. 2 nodes, largest 2.6 cm; Gr. 3 breast 1.2 cm; neo-adjuvant TAC; lump. + 16 nodes PCR
Back to Top
SagePatientAdvocates View Drop Down
Senior Member
Senior Member
Avatar

Joined: Apr 15 2009
Status: Offline
Points: 4453
Post Options Post Options   Thanks (0) Thanks(0)   Quote SagePatientAdvocates Quote  Post ReplyReply Direct Link To This Post Posted: Mar 04 2012 at 1:02am
Dear Lawana,

Welcome to our family and I am sorry you have need to be here.

You have what is called Pregnancy Associated Breast Cancer (PABC). Basically that means your cancer was found while you were pregnant or within a year of giving birth.

I am not a medical professional and will not give you medical advice but I would suggest you see an expert in PABC and BRCA. There is a wonderful Breast Medical Oncologist (BMO) at MD Anderson Cancer Center (MDACC) in Houston that I would suggest you consider seeing. Her name is Dr. Jennifer Litton. 


One of my closest friends on this site is a young woman named Natalia who posts as nmunoz. She recently attended a C4YW conference in Orlando and represented TNBC Foundation at our booth. I spoke to her last night and she told me that she went to Dr. Litton’s presentation on breast cancer and pregnancy. She was very impressed by the presentation. I will suggest to Natalia that she send you a PM and maybe the two of you can talk?


As you can see Dr. Litton had two sessions at the conference-

Workshop F | trianon II

genetics & Family risk

Jennifer K. Litton, MD, Assistant Professor of Medicine, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center Hear the latest information in the field of breast cancer genetics. Learn about the importance and role of genetic counseling – a first step toward understanding your individual and family risk. Find out about the value of creating your family pedigree and learn when genetic testing may be useful to consider. Explore methods to aid in decision- making and how to discuss your decision to be tested and your results with family members.


Workshop n | eagle room

Pregnant with Breast Cancer

Jennifer K. Litton, MD, Assistant Professor of Medicine, Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center Women who are diagnosed with breast cancer when pregnant have questions and concerns not only during their pregnancy but afterward. Learn about the accuracy of pathology reports during pregnancy, whether side effects of treatment affect the fetus, the safety of breast feeding and whether or not subsequent pregnancies are safe

to consider. Hear about the research that has been done and the registry of pregnant women with cancer that is collecting information about how breast cancer in pregnant women affects mother and child.


Lawana, MDACC is consistently ranked the number one cancer center in the U.S. They have a large breast cancer unit with 25 Breast Medical Oncologists. Also, I would suggest you get their opinion on your liver “cysts” to try to rule out any malignancy. 


http://health.usnews.com/best-hospitals/rankings/cancer


It is possible that because you are on the Hoosier trial now that MDACC will recommend that you wait a bit to see them but if you speak to one of the New Patient (NP) specialists they should be able to guide you. Please do not rely on any of my words, rather the NP person at MDACC if you decide to register for an appointment.


You can self-refer yourself to MDACC and I can walk you through how to do that. I will send you my contact info and we can talk, if you wish. I do my patient advocacy work on a volunteer basis so there will be no bills. MDACC is of course another story, financially, and the NP folks should be able to let you know if your insurance will cover the visit, if you decide to pursue it.


The other BMO, at MDACC, that I think is excellent is Dr. Ana Maria Gonzalez-Angulo. If you can see either one I believe you will be in good hands. Again, that is my unprofessional opinion.


http://faculty.mdanderson.org/Ana_Gonzalez-Angulo/Default.asp?SNID=1481996111


Lawana, whatever you decide, good luck to you.


and again, welcome to our TNBC Foundation family. I am so very, very sorry that you are dealing with this, especially as a young mom.


We will be here for you as best we can. By the way as you can see in my signature below I carry the BRCA1 mutation and passed it on to my daughter who was diagnosed seven years ago with TNBC. She is now 7+ years No Evidence of Disease (NED).


warmly,


Steve

I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates
Back to Top
confused View Drop Down
Newbie
Newbie
Avatar

Joined: Mar 04 2012
Status: Offline
Points: 3
Post Options Post Options   Thanks (0) Thanks(0)   Quote confused Quote  Post ReplyReply Direct Link To This Post Posted: Mar 04 2012 at 4:41am

I am also looking for opinions. My mom has just been diagnosed with grade 3 TNBC with 6+ nodes. Thankfully margins are clear after a mod mastectomy. She is scared and doesn't want to do chemo. She is 72 and other than the ca is healthy. If we do nothing it's a death sentence but exactly how long. She wants quality of life and feels the chemo will be too much. I have been looking thru forums and seen a 60/40 of bad side effects vs not too bad. I want at least 10 years and I know there's no guarantee but there's a chance with treatment. Very confused. Opinions?

Back to Top
SagePatientAdvocates View Drop Down
Senior Member
Senior Member
Avatar

Joined: Apr 15 2009
Status: Offline
Points: 4453
Post Options Post Options   Thanks (0) Thanks(0)   Quote SagePatientAdvocates Quote  Post ReplyReply Direct Link To This Post Posted: Mar 04 2012 at 8:04am
Dear confused,

welcome to our family. Sorry you are dealing with this but glad you found us.

If you let us know what city mom lives in maybe we can help with a referral for her? A good Breast Medical Oncologist, experienced with TNBC may be able to help her make what are very difficult decisions.

I am afraid that the standard of care for TNBC is chemo and unfortunately no one can tell you in advance if it can work or even how onerous the side effects will be for her.

Without chemo and 6+ nodes the cancer will most likely spread, systemically and probably metastasize to other organs.

I am sorry to say this but the chance of her getting your requested "ten years” is extremely remote without chemo and no one can answer your question of “how long” even of she starts chemo.

I am afraid mom is faced with very difficult choices, each having difficult consequences.

You wrote...”I know there is no guarantee but there is a chance with treatment.” I believe that is a true statement and, in my unprofessional opinion, it is important for your mom to make that choice and it is important for her to make it with as much information as possible from several knowledgeable oncologists.

Also, after hearing all the facts your mother may take a path that you don’t agree with. In that situation I think the best thing you can do is love and support her decision as best you can, even if you would like her to choose a different path. Easy for me to type and it may be difficult for you to do.

You both shall be in my prayers.

warmly,

Steve


I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates
Back to Top
Lee21 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Dec 22 2011
Location: Michigan
Status: Offline
Points: 736
Post Options Post Options   Thanks (0) Thanks(0)   Quote Lee21 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 04 2012 at 12:06pm
Confused,

Can you share with us your mother's breast cancer diagnosis? The type of information that would be helpful is seen in our signatures.  That will enable us to point you in the direction of information (and there's a lot) that is more relevant. Forum members are not practicising medical professionals and can only share personal experience.

Having said that, I would recommend that you check in on the NEW MEMBERS > OPEN ACCESS thread to see important medical information for TNBC that a number of us have posted.  To help your mom, you would need to get a handle on TNBC, the disease and treatment options.

As Steve mentioned, chemo is the only systemic therapy available to TNBC patients. However chemo comes in different flavors : types of drug, dose intensity, dose scheduling, duration etc and some are more or less debilitating than others. 

A recent study found that one of the reasons for a poorer prognosis for older women may be due to under treatment (that study did not separate out include TNBC):
http://www.medpagetoday.com/HematologyOncology/BreastCancer/31064
http://www.foxnews.com/health/2012/02/08/breast-cancer-kills-older-women-more-often/

A candid talk with your mom's treatment team would be very important. 

Lee


Edited by Lee21 - Mar 04 2012 at 12:51pm
12/9/11 @59,IDC,grade3, TNBC,3cm(MRI),SLNB0,stage IIA, BRCA1 variant
1/30/12 DD AC-T, 6/7/12 Lumpectomy, ypT1b(0.8 cm), 7/9/12 Rads x 30
11/9/12, clinical trial cisplatin/rucaparib, cisplatin-only arm
Back to Top
confused View Drop Down
Newbie
Newbie
Avatar

Joined: Mar 04 2012
Status: Offline
Points: 3
Post Options Post Options   Thanks (0) Thanks(0)   Quote confused Quote  Post ReplyReply Direct Link To This Post Posted: Mar 20 2012 at 12:15am
hello all
I am glad to say we have choosen to fight :) our mom had her 1st cycle of TAC on Thurs so far so good. Fatigue & bone pain our biggest issues...which I'll gladly take. It is such a difficult journey that we just began, I am thankful for sites like this that offer support and hope. It has been quite a journey 1st abnormal mammo in Jan bx within 10 days (only because of previous commitments) surgery done in a week from path results 1st round 1 month from surgery. I am thankful for her MD's for moving quickly, at the time it seemed too fast but it needed to be addressed.
We are fighting T2N3 TNBC tumor size 2.5cms largest lymph was >3cms cluster/clumping near the collarbone final path IDC grade 3 she will under go 6 cycles of TAC followed by 33 RADs she is 72 and because of her age no genetic profiling done


Edited by confused - Mar 20 2012 at 12:16am
Back to Top
Lillie View Drop Down
Senior Member
Senior Member
Avatar

Joined: Jul 10 2009
Location: Eastern NC
Status: Offline
Points: 3591
Post Options Post Options   Thanks (0) Thanks(0)   Quote Lillie Quote  Post ReplyReply Direct Link To This Post Posted: Mar 20 2012 at 7:03pm
Dear Confused,
I am so happy your mom has chosen to fight.  I pray the very best outcome possible for her.  You are a very special daughter and she is lucky to have you as an advocate.
 
God Bless,
Lillie
Dx 6/06 age 65,IDC-TNBC
Stage IIb,Gr3,2cm,BRCA-
6/06 L/Mast/w/SNB,1of3 Nodes+
6/06 Axl. 9 nodes-
8/8 thru 11/15 Chemo (Clin-Trial) DD A/Cx4 -- DD taxol+gemzar x4
No Rads.
No RECON - 11/2015-9 yrs NED
Back to Top
SagePatientAdvocates View Drop Down
Senior Member
Senior Member
Avatar

Joined: Apr 15 2009
Status: Offline
Points: 4453
Post Options Post Options   Thanks (0) Thanks(0)   Quote SagePatientAdvocates Quote  Post ReplyReply Direct Link To This Post Posted: Mar 20 2012 at 7:11pm
Dear confused,

Not sure why genetic profiling not done..

If they feel not informative for your mom (which, again I don’t understand) wouldn’t it possibly be informative for you?

warmly,

Steve
I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates
Back to Top
mlshaw View Drop Down
Newbie
Newbie
Avatar

Joined: Mar 20 2012
Status: Offline
Points: 10
Post Options Post Options   Thanks (0) Thanks(0)   Quote mlshaw Quote  Post ReplyReply Direct Link To This Post Posted: Mar 20 2012 at 10:21pm
Lawana
I am also fairly newly diagnosed in Jan. Stage 2b, 2 primary tumors 4 & 1 cm, sentinel nodes (6) negative.  I am doing neoadjuvent chemo (12taxol, 4carboplatin, 4 AC over 16 doses) I am on dose 11 this week. Done with carbo, it sucks. 2 taxol and 4 AC to go. So far things are going well. I have 2 kids, 7 & 9. I am a family practice physician and have been able to continue with a full time practice, some days are easier than others. I have liked the neoadjuvent chemo. My tumorrs have both been undetectable by exam since week 5. I am planning bilateral mastectomies in june, then radiation and then implants. My carboplatin is not FDA approved for breast cancer but my oncologist just finished a study and it looked good so I am on that and insurance is paying for some of it!! I want to see my kids grow up too...this kinda sucks!!!
Mandy
Back to Top
SagePatientAdvocates View Drop Down
Senior Member
Senior Member
Avatar

Joined: Apr 15 2009
Status: Offline
Points: 4453
Post Options Post Options   Thanks (0) Thanks(0)   Quote SagePatientAdvocates Quote  Post ReplyReply Direct Link To This Post Posted: Mar 20 2012 at 10:39pm
Dear Mandy,

welcome to our TNBC family and sorry you have need to be here.

Have you seen a Certified Genetic Counselor regarding getting tested for the BRCA mutation?

good luck with your treatment..

warmly,

Steve
I am a BRCA1+ grandson, son and father of women affected by breast/oc-my daughter inherited mutation from me, and at 36, was dx 2004 TNBC I am a volunteer patient advocate with SAGE Patient Advocates
Back to Top
Katdoll View Drop Down
Senior Member
Senior Member
Avatar

Joined: Mar 13 2012
Location: WA
Status: Offline
Points: 214
Post Options Post Options   Thanks (0) Thanks(0)   Quote Katdoll Quote  Post ReplyReply Direct Link To This Post Posted: Mar 20 2012 at 11:33pm
Lawana, I have a story similar to yours.  I was tested for BRCA1 in spring 2009 after a cousin was diagnosed with TN IDC.  Then I had an MRI, which showed a mass which was TN IDC.  I had bilateral mastectomy and AC/T.  My sister went down the exact same path a few months after I did.
 
Please don't despair, and as much as you can try not to let anxiety about recurrence get the best of you.  (I know that is easier said than done.)  Someone commented a few days ago that people who feel "cured" are less likely to post here because they are off living their lives.  It is true.  I rarely post, but I want to tell you about some positive outcomes, because maybe it'll help you manage your fears.  Yesterday was my two-year "cancerversary," two years since I finished treatment.  According to my oncologist it is now very unlikely I will ever have a recurrence.  My aunt is cancer free 15 years after her TN diagnosis.  My cousin is cancer free three years following her TN diagnosis.  My sister is cancer free two years since TN diagnosis.  A very good friend of mine (not BRCA+) is cancer free for eight years following a TN diagnosis.  We are all healthy, strong, active, and definitely living our lives!
 
 
Tested positive for BRCA1 mutation (187delAG) in 4/09 @ age 44; BSO 9/09; diagnosed w/TNBC in 10/09; 1 cm Stage 1 TNBC IDC, grade 3 + 1.5 cm DCIS; BMX 11/09, nodes clear; chemo (AC/T).
Back to Top
Lee21 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Dec 22 2011
Location: Michigan
Status: Offline
Points: 736
Post Options Post Options   Thanks (0) Thanks(0)   Quote Lee21 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 21 2012 at 7:16am
Hi Mandy
Thank you for sharing your story with us.
Your neoadjuvant treatment plan seems to be the most aggressive I have come across.  What was your oncologist's rationale for putting you on the 4 big guns at once?  Are you doing dose dense AC or is that q3 week cycle?
I am on cycle 4 of AC of my DD AC-T plan and this cycle I am pretty much wiped out presumably because of anemia.
Lee
12/9/11 @59,IDC,grade3, TNBC,3cm(MRI),SLNB0,stage IIA, BRCA1 variant
1/30/12 DD AC-T, 6/7/12 Lumpectomy, ypT1b(0.8 cm), 7/9/12 Rads x 30
11/9/12, clinical trial cisplatin/rucaparib, cisplatin-only arm
Back to Top
mlshaw View Drop Down
Newbie
Newbie
Avatar

Joined: Mar 20 2012
Status: Offline
Points: 10
Post Options Post Options   Thanks (0) Thanks(0)   Quote mlshaw Quote  Post ReplyReply Direct Link To This Post Posted: Mar 21 2012 at 9:09am
Lee, 
My oncologist is being very aggressive because of my age, 2 primary tumors, my genetic testing all came back normal....so she wants to be aggressive up front. I have been on weekly taxol with carboplatin every 3rd week. I will get my 11th dose of taxol tomorrow, then 1 more week of taxol and then dose dense AC every other week for 4 weeks. So far my counts are hanging in there, a little anemia is all. It is interesting to see what everyone is on. I imagine there are multiple ways to skin this stupid breast cancer cat!!! Thanks for the reply, it's nice to talk with people like me. 
Back to Top
Lee21 View Drop Down
Senior Member
Senior Member
Avatar

Joined: Dec 22 2011
Location: Michigan
Status: Offline
Points: 736
Post Options Post Options   Thanks (0) Thanks(0)   Quote Lee21 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 21 2012 at 9:23am
Mandy

I'm glad to hear you are doing well (or as well as one can be given the circumstances) -- keep us posted with your progress: we all try to learn from each other and as you say, there are so many variations on a theme.

I'm interested in the study you mentioned -- is it published?

Another issue that is of interest to many of us is the role of radiation in TNBC, specifically for those who elected to have mastectomies.  And which type of radiation: whole breast, IMRT, hypofractionated....Do you know which kind you will be getting?  I haven't crossed that bridge but will be needing to see a RT person in the coming weeks.

We're all desperately trying to do the right thing for ourselves right from the get-go but given that TNBC is such a grab bag of different subtypes, it's hard to know why the same regimen works for one person and not for another when both may have the same staging characteristics.

Lee
12/9/11 @59,IDC,grade3, TNBC,3cm(MRI),SLNB0,stage IIA, BRCA1 variant
1/30/12 DD AC-T, 6/7/12 Lumpectomy, ypT1b(0.8 cm), 7/9/12 Rads x 30
11/9/12, clinical trial cisplatin/rucaparib, cisplatin-only arm
Back to Top
 Post Reply Post Reply Page  12>
  Share Topic   

Forum Jump Forum Permissions View Drop Down

Forum Software by Web Wiz Forums® version 11.05
Copyright ©2001-2016 Web Wiz Ltd.