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MMAE side effects

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marina View Drop Down
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    Posted: Aug 15 2017 at 11:05am

Hello all, need advice on managing side effects, I'm in a phase 1 clinical trial, it's an antibody drug coagulate, and the chemo that is attached to the antibody is super powerful, it's called monomethyl auristatin E (MMAE). Just wondering if anyone has had experience with an MMAE, and how you dealt with the side effects ... I've had some really bad pain and flu like symptoms and fever.


DX IDC TNBC 10/11 age 49, Stage 2,Grade 3, 2.3cm,clear sentinal node, lumpectomy & re-excision,BRCA-,DD A/C & T, 34 rads
4/14 bone met 3X5X8cm
9/15 lung mets
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gordon15 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote gordon15 Quote  Post ReplyReply Direct Link To This Post Posted: Aug 19 2017 at 6:18pm
marina: your oncologist should answer this question, if you have nausea my wife had good luck taking Zofram, G.
wife: IDC/Lobular Stage2B 2008 lumpectomy/TAC+rads
TNBC Stage 3A/w/metaplastic/squamous Nov2015 Carboplatin-Gemzar chemo/masectomy Taxolchemo+rads 4-16
PET scan stable 9-2016/ 1-2017
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