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Metaplastic BC (MBC)

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TracyAMac View Drop Down
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    Posted: Aug 07 2011 at 5:49pm
Hello all

I am copying this post to the TNBC Talk category as Metaplastic BC (usually also TN) can occur as a primary incidence of BC. There is a longer discussion thread on this topic in the metastisis/recurrence category with some of the women on our forum who have/had MBC.
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Steve and I have been comparing notes on  articles about Metaplastic BC - (almost always TNBC too). I apologize if this is a repeat of an earlier post. The article does a good job of defining the 5 sub types of MBC, and includes pics of various cell types but as the article concludes there are some limitations with the findings as the MBC participants were at an early stage of diagnosis and treatment compared to other research participants.

http://koreanjpathol.org/upload/journal/kjp_44_6_605.pdf

Tracy in Toronto
TN&non-TN tumors April/10 Gr3&2;1 metaplastic
Rmast.1/9 nodes w/isolated t.cells
Taxotere&Cytoxan x6
Bone cancer 1980 age17;surgery&chemo AC+Methotrexate
BRCA-ve
On hormone therapy & Metformin Trial
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Olivia View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Olivia Quote  Post ReplyReply Direct Link To This Post Posted: Aug 15 2011 at 2:04am
Tracy,

Thank you for sharing. There is so little information on MBC. Hope you're doing well!   
Olivia
34yo Metaplastic TNBC 06/10 stage I grade 3 Taxol x6 AC x4 Bilat Mast with recon 0/2 nodes no rads 01/11 NED
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mindy555 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote mindy555 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 28 2011 at 6:34pm
Tracy-

Thanks for the information! Even with the limitations of study, I gleaned information in my quest for more knowledge of metaplastic BC.
Dx July 2011 56 yo
Stage I IDC,TN,Grade 3
Grew to Stage IIa- No ev of node involve- BRCA1+ chondroid metaplasia
Daughter also BRCA1+
Mass grew on Taxol
FEC 6x better
BMX 3/19/12 pCR NED
BSO 6/2012
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mags20487 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote mags20487 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 29 2011 at 2:32pm
That was interesting...good to know that they are doing some research into this rare type of BC. 
 
Maggie
Diag 8/17/2011 2cm metaplastic grade 3 bmx 8/23/2011 3/18 lymphs-Taxol x4 9/22/11 a/c x4 1/16/11.rads and recon 2012 diep 11/1/12 failed left side redone gap flap 3/5/13. lymph node transfer 5/22/13
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123Donna View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Nov 15 2013 at 8:27am
Unique clinicopathological features of metaplastic breast carcinoma compared with invasive ductal carcinoma and poor prognostic indicators
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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