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Left vs Right breast research

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mainsailset View Drop Down
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    Posted: Apr 20 2016 at 12:27pm
http://www.wltx.com/news/local/outreach/buddy-call-19/usc-researchers-make-new-breast-cancer-discovery/143532652

Columbia, SC (WLTX) - On the campus of the University of South Carolina at the School of Medicine, there is a research project being conducted unlike anything else in the country.

Dr. Ann Ramsdell and her team of researchers are working to find not only a cure for breast cancer but also how to prevent the disease altogether.

Her study involves the process of injecting cancer cells into the left and right mammary glands of the test subject. So far, the research has shown that breast cancer develops 100% of the time in the right breast. However, the left breast supresses the disease 60% of the time.

For Dr. Ramsdell, this is more than just business. Seven years ago she was diagnosed with stage three breast cancer. At that time her research was focused on cardiovascular and congenital heart disease.

But when faced with this challenge, she knew that she needed to change her focus and work on finding a cure for breast cancer.

Dr. Ramsdell and her team are specifically studying the effects of triple negative breast cancer. That form of the disease is the most aggressive and also disproportionately affects African American, Hispanic and younger women. The study's results will also have the greatest impact on women who are genetically inclined (BRCA1 or BRCA2) to developing the disease.

Dr. Ramsdell says that with each week they get closer and closer to having answers.

Her belief is that the results of this study will have an impact on all cancer research that involves dual organs.


Edited by mainsailset - Apr 20 2016 at 12:29pm
dx 7/08 TN 14x6.5x5.5 cm tumor

3 Lymph nodes involved, Taxol/Sunitab+AC, 5/09 dbl masectomy, path 2mm tumor removed, lymphs all clear, RAD 32 finished 9/11/09. 9/28 CT clear 10/18/10 CT clear
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 7:48am
Thanks Mainy!  

 "So far, the research has shown that breast cancer develops 100% of the time in the right breast. However, the left breast supresses the disease 60% of the time."

It will be interesting to see if they can find a reason as to what suppresses bc in the left breast.
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote mainsailset Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 12:24pm
Ya, that was the line that caught my attention. Since my tumor was on left side and so giant in size it makes me all the more grateful that treatment was so successful!
dx 7/08 TN 14x6.5x5.5 cm tumor

3 Lymph nodes involved, Taxol/Sunitab+AC, 5/09 dbl masectomy, path 2mm tumor removed, lymphs all clear, RAD 32 finished 9/11/09. 9/28 CT clear 10/18/10 CT clear
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Jacklin Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 9:16pm
Interesting indeed. My tumour, in my left breast, grew from a pea to bigger than a baseball in less than 3 weeks. Mainsailset, looks like our situations were very similar - thankful for you that your treatment was so successful, I'm hoping and praying for the same outcome.
Dx: Nov. 27/15, TNBC, left breast & lymph, BRCA -; Chemo: Dec 4/15 - Mar 4/16; 4 DD A/C, 3 DD Taxol; BMX/ALND: April 26/16; Stage 3C; Radiation: June 10-July 15/16; 1 cycle Xeloda: Aug 15 - 28/16
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Post Options Post Options   Thanks (0) Thanks(0)   Quote mainsailset Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 9:29pm
Jacklin, I'll be pulling for you!
dx 7/08 TN 14x6.5x5.5 cm tumor

3 Lymph nodes involved, Taxol/Sunitab+AC, 5/09 dbl masectomy, path 2mm tumor removed, lymphs all clear, RAD 32 finished 9/11/09. 9/28 CT clear 10/18/10 CT clear
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Jacklin Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 9:54pm
Thank you my friend. It is good for me to read that you've had such a good response, very encouraging for me!! Be well

Dx: Nov. 27/15, TNBC, left breast & lymph, BRCA -; Chemo: Dec 4/15 - Mar 4/16; 4 DD A/C, 3 DD Taxol; BMX/ALND: April 26/16; Stage 3C; Radiation: June 10-July 15/16; 1 cycle Xeloda: Aug 15 - 28/16
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Lillie Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 9:57pm
Mine was also on the left side.  Had a left side mastectomy and chemo (clinical trial) added gemzar.   June 9th will be 10 years since I was diagnosed. 
 
Jacklin, I'm pulling for all you girls.
 
God Bless,
Lillie
Dx 6/06 age 65,IDC-TNBC
Stage IIb,Gr3,2cm,BRCA-
6/06 L/Mast/w/SNB,1of3 Nodes+
6/06 Axl. 9 nodes-
8/8 thru 11/15 Chemo (Clin-Trial) DD A/Cx4 -- DD taxol+gemzar x4
No Rads.
No RECON - 11/2015-9 yrs NED
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Apr 21 2016 at 11:01pm
I wonder if there is any research data regarding left and right breast cancer and rates of recurrence?  
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Jacklin Quote  Post ReplyReply Direct Link To This Post Posted: Apr 22 2016 at 9:57am
Donna, that would be MOST interesting for sure. There must be something out there, I'll post it if I find it.
Dx: Nov. 27/15, TNBC, left breast & lymph, BRCA -; Chemo: Dec 4/15 - Mar 4/16; 4 DD A/C, 3 DD Taxol; BMX/ALND: April 26/16; Stage 3C; Radiation: June 10-July 15/16; 1 cycle Xeloda: Aug 15 - 28/16
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Guests Quote  Post ReplyReply Direct Link To This Post Posted: Apr 23 2016 at 9:19pm
Very interesting. One caution though. She is injecting cancer into mice. Mice are good for beginning research but they are really very different in how their bodies work. They multiple left and right breasts for ine thing.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote praying2016 Quote  Post ReplyReply Direct Link To This Post Posted: Nov 30 2016 at 3:22pm
thanks 4 sharing
Dx 39
2 daughters 3 & 6
Ki67 70%
PCr
Dx 12/5/2015, IDC, Left, 4cm, Stage IIIA, Grade 3, 3/14 nodes, ER-/PR-, HER2-
Chemotherapy 12/13/2015
Surgery 3/15/2016 Lumpectomy
Radiation Therapy 5/15/2016
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