PhD Thesis On Two Genes Involved In Hereditary Breast And Ovary Cancer Cases Treated In The Basque Country
Between 5 % and 10 % of
breast cancer
cases are hereditary, arising because the patient inherits from the
father or mother a mutation in a gene that is susceptible to causing the
illness. BRCA1 and BRCA2 have already been identified as two of the
genes to be monitored. It is estimated that 30 % of hereditary breast
cancer cases are due to mutations in one of these two genes (which
suggests, at the same time, that there are other genes involved, but
exactly how is still unknown). In any case, few of the mutations found
in BRCA1 and BRCA2 could be clearly identified as pathological. The fact
is that the mutations found were numerous; their variation even
depending on the population.
http://www.medicalnewstoday.com/articles/216957.php