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ca 27/29 blood test

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mags20487 View Drop Down
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    Posted: Mar 03 2012 at 7:35pm
I finished chemo on Dec 29th and had a pet scan 2 weeks later and blood work done then too.  My pet scan was clean but my CA 27-29 was elevated and therefore my Onc would not allow the port to be removed.  She said that it was most likely from inflammation from chemo and would retest me again in April.  That made sense at first but now I am getting paranoid that we did not get it all during chemo.  Has anyone else experienced elevated tumor markers when first finishing chemo?  Before I started chemo it was a 17 and this time it was 41.
 
Maggie
Diag 8/17/2011 2cm metaplastic grade 3 bmx 8/23/2011 3/18 lymphs-Taxol x4 9/22/11 a/c x4 1/16/11.rads and recon 2012 diep 11/1/12 failed left side redone gap flap 3/5/13. lymph node transfer 5/22/13
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LRM216 View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote LRM216 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 03 2012 at 8:53pm
Don't be paranoid - my onc won't even test for tumor markers (other than the first one prior to chemo) until 6 months after chemo ends. 
Linda - diagnosed at age 62
Diag 2/23/09 IDC 1.2 cent. IDC right breast,Stage 1, Grade 3,0/1 nodes - Triple Neg
4 DD AC every two weeks, 1 Dd Taxol, then 3 Taxotere every three weeks - rads x 33
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Mar 11 2012 at 12:19pm
Maggie,

For what it's worth, my CA 27.29 tumor marker has always been in the normal range, even when I had a recurrence.  

"Since it is not highly sensitive or specific, the CA 27.29 test can go up for reasons other than metastasis, resulting in false positives, and it may not go up when there is metastasis, resulting in false negatives."

Donna
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Allison View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Allison Quote  Post ReplyReply Direct Link To This Post Posted: Mar 11 2012 at 1:00pm
Maggie,

At my last visit I was told that we would no longer be doing blood work. I am almost 4 years out of treatment and although I will continue to see him every 6 months, he said that the standard had changed and that tumor markers were so highly unreliable that they were next to useless. He said that in all of his years of practice he has not found them to be an unreliable indicator. My previous oncologist never shared my tumor marker numbers with me - always just assured me that they were fine. 

Wishing you peace of mind!

Allison

Donna - wonder if there are any articles out there regarding standards of care? 
9/07 IDC, trip neg, BRAC-, Lumpectomy with SNB (all clear) 10/07, FEC & Taxatere 11/07 - 2/08, 32 rads, 3/08 - 5/08.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote debB Quote  Post ReplyReply Direct Link To This Post Posted: Mar 11 2012 at 9:25pm
Hi Maggie,

My oncologist does not test for tumor markers. If I recall correctly, he said they only have about a 50% reliability for detecting recurrance. I remember the 50% because he said he could flip a coin and be just as accurate predicting if I had a recurrance!

Deb
Dx 4/29/11, 46 yrs old, 3.9 cm tumor, Stg 2 Grade 3 chemo 4 rounds DD AC, 12 weekly taxol, finish. Lumpectomy, 2mm residual tumor. 37 rounds rads completed. Cisplatin/PARP trial
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Mar 11 2012 at 10:04pm
Maggie,

Your CA 27.29 test results are still close to normal.  I think they are looking for big changes in the results.  My friend with a gynecological cancer gets the CA 15.3 test.  Her levels went from 13 to 125.  


DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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