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Are Chemo Side Effects Cumulative?

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Asovey View Drop Down
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    Posted: Jan 16 2018 at 1:26pm
Hi Everyone:  Time to call on all your expertise again!

I am getting ready to have my second A/C infusion on Friday.  The first one on January 5th went well and side effects were minimal - thanks to medications - and manageable.  I have been told that side effects are cumulative - but HOW cumulative?  This has me scared.  Will they increase the pre-meds because this is #2 infusion?

Ann
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Post Options Post Options   Thanks (1) Thanks(1)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Jan 17 2018 at 7:56am
Ann,

I didn't notice chemo was cumulative.  It could be with something like Taxol/Taxotere where neuropathy side effects may get worse.
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Asovey Quote  Post ReplyReply Direct Link To This Post Posted: Jan 17 2018 at 6:30pm
Thanks Donna!  I sure hope that is true!

Ann
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Kellyless Quote  Post ReplyReply Direct Link To This Post Posted: Jan 18 2018 at 11:13am
Anemia will kick in at some point and you may feel that.  A woman ahead of me in treatment warned me, she said that you start feeling extra tired, then one day you'll do some normal exertion at home and your heart will pound and you'll feel a bit out of breath - she thought she was having a heart attack.  Sure enough, after a few treatments I gathered laundry room to room, walked across the house and BAM - my heart pounded, I felt a bit breathless.  Test confirmed I'd hit anemic.  There's no shot for red blood cells (there was for a time, but then they found out it caused cancer), like the Neulasta for white cells.  Pill form iron doesn't work I was told, you need to eat all the iron rich foods you can.  I got so anemic this last time I was eating steak for breakfast when I could stomach it.  If anemia gets too bad they'll have you go to the hospital for a blood transfusion - ick.
I iced my hands and feet both times I did Taxol and I have less neuropathy than anyone I've met that did NOT do ice.  Definitely worth it, since it can be permanent!
IDC, 2.2 cm, Stage IIb,lumpectomy 1/30/09 ACx4,Tx4 36 rads
6/1/17 Local recurrence same breast, same spot 1.8cm Carb.4x every 3 wks, Taxol 12x once wk. Dbl Mast. PCR!! Reconstruction fail, NED!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Asovey Quote  Post ReplyReply Direct Link To This Post Posted: Jan 18 2018 at 12:38pm
Thanks for this info Kelly. I will be on watch for anemia. So far red blood cell count is OK. It has gone down some, but not much. How exactly did you ice your hands and feet? I asked about that when I got my last chemo and the nurses had not heard of it.

Thanks - Ann
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Post Options Post Options   Thanks (0) Thanks(0)   Quote ClistaR Quote  Post ReplyReply Direct Link To This Post Posted: Jan 25 2018 at 2:02am
I didn't notice the AC side effects being cumulative, I felt tired and nauseated the entire time. With the taxol I didn't notice any neuropathy until about half way through and 2 weeks out of my last infusion it is still significant. 

I used cold mitts and booties that the facility provided during the taxol infusions. Not sure if it helped or not but figured it was worth a try.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Asovey Quote  Post ReplyReply Direct Link To This Post Posted: Jan 25 2018 at 8:44am
Thanks for your response Clista. Just had my second AC infusion and I don’t think it is any worse than the first one. Really, I have been very lucky. I am tired with occasional nausea. I know I am lucky! Hope it s that way.

Of course, hair is almost gone, but I expected that. I will start Taxol and Carboplatin at the beginning of March. I asked about the mits and booties and the infusion nurses looked at me like I was from Mars. I am going to,see if they will get them. I know they have the cold caps.

Congratulations on completing chemo! Can’t wait till I am at that spot!

Ann
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Warriorkat Quote  Post ReplyReply Direct Link To This Post Posted: Mar 12 2018 at 1:30pm
I’ll have my 4th A-C this Friday. I have noticed increased heartburn and increased loss of appetite each time. It just lasts a day or two longer each treatment but by the start of week two I’m much better. A bit more tiredness too but not severe. So far I haven’t had nausea and though I took the premeds and steroids I did not take any additional Zofran and was fine. It just constipated me so I did without. It seems we all have different experiences. I did start a pre/probiotic which I think helps.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Kellyless Quote  Post ReplyReply Direct Link To This Post Posted: Mar 14 2018 at 9:35am
Try papaya enzyme tablets for the heartburn, you can get them at the health food store or online.  They taste pleasant, you can chomp as many as you like - worked better than Tums or Rolaids for me and the Drs were all for it.

Congrats on getting thru - WHOOP! 
IDC, 2.2 cm, Stage IIb,lumpectomy 1/30/09 ACx4,Tx4 36 rads
6/1/17 Local recurrence same breast, same spot 1.8cm Carb.4x every 3 wks, Taxol 12x once wk. Dbl Mast. PCR!! Reconstruction fail, NED!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Warriorkat Quote  Post ReplyReply Direct Link To This Post Posted: Mar 14 2018 at 9:37am
I will try that. Thanks!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote gordon15 Quote  Post ReplyReply Direct Link To This Post Posted: Mar 15 2018 at 10:23pm
My wife , since shes had quite a disruption in digestion, in the last many years, takes these:

(ENZYMES)

https://www.amazon.com/gp/product/B002S1U7RU/ref=oh_aui_detailpage_o05_s00?ie=UTF8&psc=1

https://www.amazon.com/gp/product/B0009EXOTQ/ref=oh_aui_detailpage_o09_s00?ie=UTF8&psc=1   ;

She takes "FoodScience of Vermont Superior Enzymes " when eating beef/meat (Amazon) too

(FIBER SUPPLEMENTS) (for constipation)

https://www.amazon.com/gp/product/B00B8YUQXS/ref=oh_aui_detailpage_o05_s01?ie=UTF8&psc=1
(unsweetned) powder



also: (sweetened )orange flavor/ they might have artif sweetened)powder:

we buy this at RiteAid, it's called " Multihealth fiber suppliment psyllium husk 3.4gm" it's their own brand orange flavor, sweetened, it only takes a Tablespoon a day or less(not Metamucal brand name)

Edited by gordon15 - Mar 15 2018 at 10:52pm
wife: IDC/Lobular Stage2B 2008 lumpectomy/TAC+rads
TNBC Stage 3A/w/metaplastic/squamous Nov2015 Carboplatin-Gemzar chemo/masectomy Taxolchemo+rads 4-16
PET scan stable 9-2016/ 1-2017
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