It is becoming increasingly clear that chronic inflammation is the root cause of many serious illnesses - including heart disease, many cancers, andAlzheimer's disease. We all know inflammation on the surface of the body as local redness, heat, swelling and pain. It is the cornerstone of the body's healing response, bringing more nourishment and more immune activity to a site of injury or infection. But when inflammation persists or serves no purpose, it damages the body and causes illness. Stress, lack of exercise, genetic predisposition, and exposure to toxins (like secondhand tobacco smoke) can all contribute to such chronic inflammation, but dietary choices play a big role as well. Learning how specific foods influence the inflammatory process is the best strategy for containing it and reducing long-term disease risks. (Find more details on the mechanics of the inflammation process and the Anti-Inflammatory Food Pyramid.) The Anti-Inflammatory Diet is not a diet in the popular sense - it is not intended as a weight-loss program (although people can and do lose weight on it), nor is it an eating plan to stay on for a limited period of time. Rather, it is way of selecting and preparing foods based on scientific knowledge of how they can help your body maintain optimum health. Along with influencing inflammation, this diet will provide steady energy and ample vitamins, minerals, essential fatty acids dietary fiber, and protective phytonutrients.
You can also adapt your existing recipes according to these anti-inflammatory diet principles:
Minimize your consumption of processed foods and fast food.
Eat an abundance of fruits and vegetables.
Caloric Intake
Most adults need to consume between 2,000 and 3,000 calories a day.
Women and smaller and less active people need fewer calories.
Men and bigger and more active people need more calories.
If you are eating the appropriate number of calories for your level of activity, your weight should not fluctuate greatly.
The distribution of calories you take in should be as follows: 40 to 50 percent from carbohydrates, 30 percent from fat, and 20 to 30 percent from protein.
Try to include carbohydrates, fat, and protein at each meal.
Carbohydrates
On a 2,000-calorie-a-day diet, adult women should consume between 160 to 200 grams of carbohydrates a day.
Adult men should consume between 240 to 300 grams of carbohydrates a day.
The majority of this should be in the form of less-refined, less-processed foods with a low glycemic load.
Reduce your consumption of foods made with wheat flour and sugar, especially bread and most packaged snack foods (including chips and pretzels).
Eat more whole grains such as brown rice and bulgur wheat, in which the grain is intact or in a few large pieces. These are preferable to whole wheat flour products, which have roughly the same glycemic index as white flour products.
Eat more beans, winter squashes, and sweet potatoes.
Cook pasta al dente and eat it in moderation.
Avoid products made with high fructose corn syrup.
Fat
On a 2,000-calorie-a-day diet, 600 calories can come from fat - that is, about 67 grams. This should be in a ratio of 1:2:1 of saturated to monounsaturated to polyunsaturated fat.
Reduce your intake of saturated fat by eating less butter, cream, high-fat cheese, unskinned chicken and fatty meats, and products made with palm kernel oil.
Use extra-virgin olive oil as a main cooking oil. If you want a neutral tasting oil, use expeller-pressed, organic canola oil. Organic, high-oleic, expeller pressed versions of sunflower and safflower oil are also acceptable.
Avoid regular safflower and sunflower oils, corn oil, cottonseed oil, and mixed vegetable oils.
Strictly avoid margarine, vegetable shortening, and all products listing them as ingredients. Strictly avoid all products made with partially hydrogenated oils of any kind. Include in your diet avocados and nuts, especially walnuts, cashews, almonds, and nut butters made from these nuts.
For omega-3 fatty acids, eat salmon (preferably fresh or frozen wild or canned sockeye), sardines packed in water or olive oil, herring, and black cod (sablefish, butterfish); omega-3 fortified eggs; hemp seeds and flaxseeds (preferably freshly ground); or take a fish oil supplement (look for products that provide both EPA and DHA, in a convenient daily dosage of two to three grams).
Protein
On a 2,000-calorie-a-day diet, your daily intake of protein should be between 80 and 120 grams. Eat less protein if you have liver or kidney problems, allergies, or autoimmune disease.
Decrease your consumption of animal protein except for fish and high quality natural cheese and yogurt.
Eat more vegetable protein, especially from beans in general and soybeans in particular. Become familiar with the range of whole-soy foods available and find ones you like.
Fiber
Try to eat 40 grams of fiber a day. You can achieve this by increasing your consumption of fruit, especially berries, vegetables (especially beans), and whole grains.
Ready-made cereals can be good fiber sources, but read labels to make sure they give you at least 4 and preferably 5 grams of bran per one-ounce serving.
Phytonutrients
To get maximum natural protection against age-related diseases (including cardiovascular disease, cancer, and neurodegenerative disease) as well as against environmental toxicity, eat a variety of fruits, vegetables and mushrooms.
Choose fruits and vegetables from all parts of the color spectrum, especially berries, tomatoes, orange and yellow fruits, and dark leafy greens.
Choose organic produce whenever possible. Learn which conventionally grown crops are most likely to carry pesticide residues and avoid them.
Drink tea instead of coffee, especially good quality white, green or oolong tea.
If you drink alcohol, use red wine preferentially.
Enjoy plain dark chocolate in moderation (with a minimum cocoa content of 70 percent).
Vitamins and Minerals The best way to obtain all of your daily vitamins, minerals, and micronutrients is by eating a diet high in fresh foods with an abundance of fruits and vegetables. In addition, supplement your diet with the following antioxidant cocktail:
Vitamin C, 200 milligrams a day.
Vitamin E, 400 IU of natural mixed tocopherols (d-alpha-tocopherol with other tocopherols, or, better, a minimum of 80 milligrams of natural mixed tocopherols and tocotrienols).
Selenium, 200 micrograms of an organic (yeast-bound) form.
Mixed carotenoids, 10,000-15,000 IU daily.
The antioxidants can be most conveniently taken as part of a daily multivitamin/multimineral supplement that also provides at least 400 micrograms of folic acid and 2,000 IU of vitamin D. It should contain no iron (unless you are a female and having regular menstrual periods) and no preformed vitamin A (retinol). Take these supplements with your largest meal.
Women should take supplemental calcium, preferably as calcium citrate, 500-700 milligrams a day, depending on their dietary intake of this mineral. Men should avoid supplemental calcium.
Other Dietary Supplements
If you are not eating oily fish at least twice a week, take supplemental fish oil, in capsule or liquid form (two to three grams a day of a product containing both EPA and DHA). Look for molecularly distilled products certified to be free of heavy metals and other contaminants.
Talk to your doctor about going on low-dose aspirin therapy, one or two baby aspirins a day (81 or 162 milligrams).
If you are not regularly eating ginger and turmeric, consider taking these in supplemental form.
Add coQ10 to your daily regimen: 60-100 milligrams of a softgel form taken with your largest meal.
If you are prone to metabolic syndrome, take alpha-lipoic acid, 100 to 400 milligrams a day.
Water
Drink pure water, or drinks that are mostly water (tea, very diluted fruit juice, sparkling water with lemon) throughout the day.
Use bottled water or get a home water purifier if your tap water tastes of chlorine or other contaminants, or if you live in an area where the water is known or suspected to be contaminated.
Note: If you are currently getting treatment, always check with your doctor first before taking any supplements.
Preventing Inflammation, Part 2: Supplements
In addition to eating an anti-inflammatory diet, the following four herbs and medications have powerful anti-inflammatory effects.
Ginger. Dried, powdered ginger is a potent anti-inflammatory agent, and capsules are readily available in health food stores. Choose products that are standardized for their content of active components, and start with one gram per day (usually two capsules), taken after a meal to avoid stomach irritation. There is no toxicity and you can stay on it indefinitely.
Turmeric. The principal ingredient in mild yellow prepared mustard and in some curries, turmeric has excellent anti-inflammatory properties. This bright spice may also have a specific preventive effect against Alzheimer's disease and reduce the risk of cancer. Take a whole extract of turmeric, such as those prepared by the process of “supercritical extraction" which uses liquefied carbon dioxide to extract turmeric's beneficial components.
Aspirin (acetylsalicylic acid). This time-honored pain medication offers a great many health benefits, including down-regulation of inflammation, decreased risk of heart attack, blood-thinning effects and reduced risk of some cancers. There is a downside to aspirin - a potential risk of irritation and bleeding of the lining of the stomach and lower GI tract - but in general the health benefits of low-dose aspirin regimens greatly outweigh risks. Talk with your doctor to see if a daily aspirin is right for you.
NSAIDS (non-steroidal anti-inflammatory drugs) other than aspirin. These include ibuprofen, Advil, Motrin and related products. Ibuprofen reduces risk ofAlzheimer's disease to a greater degree than aspirin, but has the same risks of gastrointestinal irritation and bleeding. Dr. Weil recommends daily use only for those with significant family histories of Alzheimer's, or with symptomatic inflammation (such as from arthritis or bursitis), but be sure to speak with your doctor first.
Hi Donna, Thank you for posting the diet information, very nice summary. To complement yours, I posted a number of links to articles and sites in the New members > Open Access site (some articles are indeed open access) on diet, dietary supplements, physical activity. Please feel free to post there if you are so inclined. - Lee
Flaxseed is an excellent source of lignans, a type of phytoestrogens (see articles under lignans and breast cancer in OPEN ACCESS). At the recommendation of my nutritionist from the cancer center, I have added a tablespoon of milled flaxseeds to my soy yogurt every day (although my med onc is a bit leery about "too much soy").
For centuries, spices have been used as medicines. Today their healing potential is again being rediscovered, especially curcumin. In one recent medical study, curcumin was found to be better than conventional medications at relieving the pain associated with rheumatoid arthritis.
Curcumin is derived from the spice turmeric. Turmeric is a member of the ginger plant family. The ginger family is comprised of more than 1,300 members and many are considered medicinal plants including ginger, turmeric, melegueta pepper and cardamom. Although many studies have demonstrated the anti-inflammatory properties of curcumin, good medical studies comparing the effectiveness of curcumin to current medications are limited.
Medical research with curcumin or its parent, turmeric, is increasing. These studies suggest that curcumin and turmeric may have benefits for a number of medical conditions including many cancers, skin conditions like psoriasis, Alzheimer's disease, irritable bowel disease, autoimmune diseases and chronic pain.
One specific autoimmune disease often associated with chronic pain is rheumatoid arthritis. An autoimmune disease is a medical condition in which the body attacks itself. RA is most commonly expressed as pain and damage to the joints, especially in the hands. Severe RA can be life threatening and can damage many organs, including the heart and liver. Fortunately RA is relatively rare, affecting only about 1 percent of the population. For unknown reasons, women are affected three times more often than men.
Anti-inflammatory medications are used to help with the pain, but long-term use can damage the kidneys and increase the risk of stomach ulcers and bleeding. Safer pain-relieving products are needed for long-term use. Curcumin may be an option.
In the medical journal Phytotherapy Research, two researchers, one from the Nirmala Medical Centre in India and the other from Baylor Research Institute and the Sammons Cancer Center in Texas, published their work on curcumin. They showed that curcumin is more effective than the common anti-inflammatory medication diclofenac for the pain associated with mild, active RA.
In the study, RA patients taking curcumin for eight weeks had a 44 percent reduction in pain symptoms, while those taking diclofenac had a 42 percent reduction. It may not seem like there is a big difference between curcumin and diclofenac, but the difference was significant.
Interestingly, the curcumin group also had a greater reduction in overall inflammation (RA may have slightly improved) compared to the diclofenac group. There also were no adverse events with curcumin.
This was an initial study, but was well controlled and randomized. It is a good study and the results cannot be dismissed. Larger clinical trials are needed to confirm these results.
One drawback to curcumin is that, by itself, it is poorly absorbed. Black pepper can help increase absorption. Over-the- counter curcumin may or may not contain black pepper.
Although curcumin appears to be very safe, interactions with medications are always possible. RA is a serious disease and I strongly recommend consulting a medical doctor before using curcumin to treat RA symptoms.
My savvy GYN explained more about Tumeric (Curcumin) and its advantages.. even after I explained that it's not beneficial in BRCA+ according to the Edge Cam protocol.
I wish I could quote him. Unfortunately I'm still cloudy with residual chemo brain. It was impressive enough to add it back to my regimen at 500 mg taken 2x each day. I use Doctor's Choice brand with black pepper fruit extract from the protocol. He also believes so strongly in fish oil. I like to alternate flaxseed oil and fish oil supplements, as they both have impressive benefits.
Thanks for all of the useful information!
xxxxooo
Dx July 2011 56 yo Stage I IDC,TN,Grade 3 Grew to Stage IIa- No ev of node involve- BRCA1+ chondroid metaplasia Daughter also BRCA1+ Mass grew on Taxol FEC 6x better BMX 3/19/12 pCR NED BSO 6/2012
What type of fish oil do you use? I'm looking for one that says it's purified but can't find a source. My husband has problems with some arthritis and knee inflammation. He had surgery last year for a torn meniscus in one knee and it's been bothering him again. He started taking glucosomin/chondroitin and says it's helping. I'm going to give him some of my tumeric capsules with bioperine (black pepper) and see if it helps with the inflammation.
Donna
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09) 11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15
I've been following most of Weil's advice for a couple months and I find it's a very healthy and reasonable diet. There's plenty to enjoy. It's easier to maintain weight as well. He advocates not eating a lot of bread, even whole grain. That's the most challening part for me and I probably eat more than he would reocmmend. Cooked intact grains are better according to Weil, and they are delicious. My favorites are hulled (not pearled) barkey and farro. You can make amazing grain salads with cooked grains, olive oil, lemon juice, herbs, and cut up fresh or roasted vegetables.
Someone asked about fish oil. The dietician at my cancer center recommended Nordic Naturals, and that's what I use. It's a lot more expensie than others, but she said this is one supplement where you should get the best because of mercury levels in fish. You want a product that is really well purified. Nordic Naturals has different varieties. I use "ultimate omega" as it has the most fish oil. I stock up when it goes on sale at Whole Foods and my local co-op.
You can make your own turmeric capsules. You'll save a ton of money plus you can use organic turmeric. Whole Foods and health food stores carry bulk turmeric that is super cheap, plus empty capsules and kits for filling the capsules. Add ground pepper to the turmeric before filling the capsules. According to Weil, pepper is needed for your body to absorb the turmeric.
Tested positive for BRCA1 mutation (187delAG) in 4/09 @ age 44; BSO 9/09; diagnosed w/TNBC in 10/09; 1 cm Stage 1 TNBC IDC, grade 3 + 1.5 cm DCIS; BMX 11/09, nodes clear; chemo (AC/T).
We use Nordic Naturals too. I get it on Amazon. To get it locally, although I would like to support the local store, would be at least a third more money. The ultimate omegas are lemon flavored inside the capsule, apparently so that if you get fish burps, they will be lemony tasting. Interestingly, I get the strawberry ones for my daughter and I DO get burps from those, they are not fishy burps tho, they are strawberry burps. But the adult ones in lemon, I do not get any burps. Apparently freezing them helps for no burps but I don't freeze them.
I can get the turmeric powder too, but it was clear that there was no way I was going to get it into the capsules without it being a collosal, never ending mess. Katdoll, can you comment on the kit for filling the capsule, I have not heard of anything like that.
What is the ratio of turmeric to pepper you use?
I'll look into the Doctor's Choice, too.
Thanks guys.
IDC dx 4/24/09, Age 40
Two surgeries, three tumors: 1.4cm,4mm,2mm; Ki67=75
Stage 1, no node involvement, clean margins
BRCA 1/2 negative,
Chemo: AC dose dense then Taxol dose dense, then rads
If you go to amazon.com and do a search on "capsule filler," you'll come up with choices for empty capsules and the "machine" to fill them. My guess is you'd find these products at Whole Foods and health food stores as well. I've seen them at my local food co-op. I actually have not used a machine yet so I don't have a recommendation for which one to use or how well they work. I'm still on my first batch of turmeric capsules, which I made by hand. It was really fiddly and I make a mess, so I'm going to get a machine soon. There are different size capsules. I used "O" this time around, but I may switch to the next bigger size, which I think is "OO". (The sizing on these things makes no sense to me.)
When you do this, I suggest laying out newspaper and cleaning up any scattered turmeric with a broom rather than sponge, because turmeric is a very strong dye when wet. I did my little project on a French tablecloth that has a supposedly impermeable coating and cleaned up with a sponge. It WAS blue, and now it is blue with a giant green area, where the yellow turmeric absorbed into the blue cloth.
As to pepper, your guess is as good as mine. Weil doesn't provide any guidance on that. I had about a half cup of turmeric and I ground in pepper till my hand ached, LOL. It was enough that there was a strong smell of pepper, probably a tablespoon. (Next time I will buy pre-ground pepper.)
I try to take two capsules twice a day with meals.
Tested positive for BRCA1 mutation (187delAG) in 4/09 @ age 44; BSO 9/09; diagnosed w/TNBC in 10/09; 1 cm Stage 1 TNBC IDC, grade 3 + 1.5 cm DCIS; BMX 11/09, nodes clear; chemo (AC/T).
Thanks for mentioning the fish oil you take ladies. I'm always on the lookout for the purist form, as mercury levels and other toxins can be detrimental.
Here's a link and the one I take. Donna I dropped you a mail. I might order the Nordic Naturals for a comparison...
(sorry, for some reason you have to copy and paste to open..)
Edited by mindy555 - Apr 22 2012 at 11:22pm
Dx July 2011 56 yo Stage I IDC,TN,Grade 3 Grew to Stage IIa- No ev of node involve- BRCA1+ chondroid metaplasia Daughter also BRCA1+ Mass grew on Taxol FEC 6x better BMX 3/19/12 pCR NED BSO 6/2012
The reviews for Nordic are very good. I'm supporting a local source who's doctor is in my city. Their marine fish oil Omega product has been evaluated by an outside source, tested 3x and are supposedly very pure. They don't create any burping up fish taste and contain a natural lemon flavor and none of the upset stomach of cheaper versions.
However, I checked pricing on Nordic Naturals, and they're actually cheaper on Amazon if you buy in quantity than what I'm using.
Thanks for the good info ladies! Mindy
Dx July 2011 56 yo Stage I IDC,TN,Grade 3 Grew to Stage IIa- No ev of node involve- BRCA1+ chondroid metaplasia Daughter also BRCA1+ Mass grew on Taxol FEC 6x better BMX 3/19/12 pCR NED BSO 6/2012
Wanted to add- be sure to check expiration dates on any Omega Fish Oil. They can be refrigerated, however you want to make sure to take by the expiration IMO.
Dx July 2011 56 yo Stage I IDC,TN,Grade 3 Grew to Stage IIa- No ev of node involve- BRCA1+ chondroid metaplasia Daughter also BRCA1+ Mass grew on Taxol FEC 6x better BMX 3/19/12 pCR NED BSO 6/2012
I wanted to mention that I take bitter melon supplements daily, which have also been shown to be an effective supplement that can help reduce the risk of recurrences. They is a lot of information available (here is one article - http://www.sciencedaily.com/releases/2010/02/100223131956.htm) I urge you to look into it. I have also tried eating the real thing, but it is not too pleasant tasting.
Want to prevent inappropriate inflammation, reduce the risk of age-related diseases, and promote optimum health at any age? Then try an anti-inflammatory diet. By aiming for variety, including as much fresh food as possible, minimizing processed and fast foods, and making fruits and vegetables the foundation of your meals, you will be well on your way. Here are some simple steps to get you started:
Step One: Look at your carbs. The majority of carbohydrates in your diet should be in the form of less-refined, less-processed foods with a low glycemic load. You can do this by replacing your snack foods (typically made with wheat flour and sugar) with whole grains, beans, winter squashes and sweet potatoes.
Step Two: Replace your cooking oil. Instead of safflower, soy, and sunflower oils, corn oil, cottonseed oil, mixed vegetable oils, or margarine, use extra-virgin olive oil as your main cooking oil (for a neutral-tasting oil, use cold-expeller-pressed, organic canola oil).
Step Three: Decrease your consumption of animal protein. Except for fish (such as omega-3 rich salmon) and organic dairy products, animal-derived protein should be limited. You can easily replace meat with vegetable protein such as beans, legumes and whole soy foods.
Step Four: Eat more fiber. Start slow and build gradually to eat 40 grams of fiber a day, simple to do if you increase your consumption of fruit, especially berries, vegetables and whole grains.
This diet has done great things for my heart health. I've followed it for a year - lots of plants, lots of whole grains, nuts, beans, healthy fats (avocado, walnuts, olive and walnut oil), fish. Very little meat. But I am not super strict about it and allow room for treats outside the diet. My cholesterol skyrocketed 40 points in the year after my ovaries were removed. After this past year of a (mostly) anti-inflammatory diet, my total cholesterol went down ten points and my HDL (the good cholesterol) went up 11 points.
Tested positive for BRCA1 mutation (187delAG) in 4/09 @ age 44; BSO 9/09; diagnosed w/TNBC in 10/09; 1 cm Stage 1 TNBC IDC, grade 3 + 1.5 cm DCIS; BMX 11/09, nodes clear; chemo (AC/T).
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