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maryjahn View Drop Down
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Post Options Post Options   Thanks (0) Thanks(0)   Quote maryjahn Quote  Post ReplyReply Direct Link To This Post Posted: Oct 19 2009 at 9:42am
Hi Donna,
 
I hope this info isn't redundant--I stumbled upon this article looking for something else:
 

Vitamin A and vitamin D3 inhibit breast cancer cell division and can induce cancer cells to differentiate into mature, non-cancer cells. Vitamin D3 works synergistically with tamoxifen to inhibit breast cancer cell proliferation. Breast cancer patients should take 4,000 to 6,000 IU of vitamin D3 every day on an empty stomach. Water-soluble vitamin A can be taken in doses of 100,000 IU to 300,000 IU every day. Monthly blood tests are needed to make sure toxicity does not occur in response to these relatively high daily doses of vitamin A and vitamin D3. After six months, the doses of vitamin D3 and vitamin A can be reduced.

In one study, vitamin E succinate, a derivative of fat-soluble vitamin E, inhibited growth and induced apoptic cell death in estrogen receptor-negative human breast cancer cell lines. The study concluded that vitamin E succinate may be of clinical use in the treatment of aggressive human breast cancers, particularly those that are resistant to anti-estrogen therapy.

Estrogen receptor-negative breast cancer patients should consider taking 1,200 IU of vitamin E succinate a day.

Soy extracts have become very popular in the last few years as an adjuvant (assisting) cancer therapy. However, there are some cancer patients who should not use soy, or who are less likely to benefit from soy.

Cancer patients undergoing radiation therapy should not take soy supplements one week before, during, and one week after being treated. Soy inhibits protein kinase C activity in cancer cells. Since cancer cells use protein kinase C for energy production, inhibiting this enzyme is usually desirable. Radiation therapy, on the other hand, depends on protein kinase C to help generate free radicals that kill cancer cells. It's possible, therefore, that large amounts of genistein in cancer cells could protect them against radiation-induced free-radical-mediated destruction.

In studies, genistein has shown anti-angiogenesis effects. Angiogenesis (new blood vessel growth) is a key step in tumor growth, invasion and metastasis. To date, a number of anti-angiogenic agents have been identified. In animal models, treatment with angiogenesis inhibitors has proven anti-tumor effects. Early clinical experience with angiogenic inhibitors indicates that optimal anti-angiogenic therapy will likely be based on the long-term administration of genistein to cancer patients as an adjunct to surgery and conventional chemotherapy. Genistein is one of the more potent nutritional anti-angiogenesis agents.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote maryjahn Quote  Post ReplyReply Direct Link To This Post Posted: Oct 19 2009 at 11:06am
That's wonderful Nancy--thank you!
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Oct 19 2009 at 1:37pm
Nancy,

Thanks for the links on the talk forum and asking your friend about D3 and surgery.  I was pretty disapointed to be told not to take it and having my levels at only 19Cry.  Do you think the ZRT in-home tests are as accurate as the blood tests the doctor's office performs?  Just wondering. . . 

Mary,

I ready your posts.  Can you tell me what is genistein?  Not sure if I've heard of it.

Donna
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 19 2009 at 5:48pm
Donna,
 
I just got off the phone with my friend. She said that her surgeon told her to go off everything 3 days before her surgery. I forgot to ask when she went back on themEmbarrassed She is my water aerobics instructor, and she called me to ask if I would give the class tomorrow. Her grandchildren are ill. I will call her again tomorrow. I promise.Wink
 
From what the vitamin D council newsletters state...their test kits are very reliable. My blood work was sent to Mayo Clinic, and I had it drawn at the hospital here. I am sure you can start taking it after your surgery. A week or so could not make that much difference Donna. 
 
Lori went to her GYN today (also mine and 2 other daughter's and 3 granddaughters), and she was so pleased to hear that Lori was on the biodentical hormones. The only point on which she disagreed with Suzanne Somers, was on the rythmic versus the static dose. I was truly surprised at her reaction, as the Dr. is at a very rural hospital, town of about 2500.
 
They are really pushing the D3, and she said that Lori's levels of 82.6 are great and it would be fine even in the 90's. Finally...!! The natural news sites have been stating that for well over 2 years now. Conventional medicine is finally catching up!!
 
Lori feels /knows that her D levels were down before because her hormones were not balanced.
 
ok...hopefully Mary will reply to you.
Hugs,
Nancy
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DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote maryjahn Quote  Post ReplyReply Direct Link To This Post Posted: Oct 19 2009 at 9:28pm
Phytochemical:
Genistein

Synonyms: 5, 7-dihydroxy-3- (4-hydroxyphenyl)-4H-1-benzopyran-4-one, 4', 5, 7-trihydroxyisoflavone

Properties: Genistein has may health benefits and works on several fronts: it acts as a phytoestrogens, antioxidant, anti-cancer agent and it could help people with metabolic syndrome.

Estrogenic effect

The estrogenic activity of genistein has been confirmed in many studies. Of all the isoflavones, genistein has the strongest estrogenic activity. The estrogenic effect of genistein may explain its protective action against osteoporosis and its possible effect on body weight reductions. Genistein is also used to ease menopause symptoms, such as hot flushes.

Antioxidant

Genistein is a strong antioxidant. Genistein removes damaging free radicals and reduces lipid peroxidation. Only oxidized LDL cholesterol is absorbed by the arterial cells and prevention of the oxidation of LDL cholesterol will reduce the risk for arteriosclerosis. Gensistein prevents the formation of hearth attacks and strokes by acting as anticlotting agent. Genistein increases the activity of other antioxidant enzymes such as glutathione peroxidase, superoxide dismutase and glutathione reductase. Studies have shown that genistein can also influence the growth of cells which are not hormone-dependent. Genistein seems to inhibit the activity of tyrosine kinase, which plays an important role in cell growth. Reduction of tyrosine activity will result in a reduced cancer risk.

Anticancer

Genistein seems to reduce the risk for some hormone related cancers, principally breast cancer and prostate cancer. Epidemiological studies show that consumption of isoflavones may protect against breast and prostate cancer. High dietary intake of soy products China and Japan are linked with low incidence of these cancers. There are lots of theories to explain the anti-cancer action of genistein: inhibition of angiogenesis, inhibition of tyrosine kinases, antioxidant property, and anti-estrogen action (it is known that estrogen increases risk for certain cancers). Genistein binds with estrogen receptors, preventing the estrogen from binding and initiating cancer growth.

Facts about Genistein: The main source of genistein is the glucoside genistin. Before genistein can act it first needs to be released from genistin. This normally happens in the stomach (acid hydrolysis) and intestine (action of bacterial enzymes). Some genistein supplements contain genistein which has been hydrolysed in a chemical process.

Description: Genistein is an isoflavone belonging to the group of flavonoids. Because of this similarity of the structure of genistein to that of estrogen genistein is also a phytoestrogens, together with daidzein. Genistein is the aglycone (without sugar component) of the glycoside genistin.

Distribution: The main source of genistein are soybeans. Other legumes, such as chickpeas, contain small amounts of genistein.

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 21 2009 at 8:21am
Mary,
 
In a search for BHRT, I found links for this one antiaging specialist in CA. In Lori's path report she tested 95% for the p53 gene mutation, and 85% for the k1-67so these links were of special interest to her also.
Nancy
 
Nancy
DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Oct 21 2009 at 2:07pm
Nancy and Mary,

Thanks for all the information.

Donna
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 21 2009 at 2:27pm
Donna,
 
I found this article in the one link which I posted as to Genistein.
Nancy
 
Nancy
DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 26 2009 at 9:05pm
Donna,
 
I have this link for you and it is from LifeExtension magazine. A list of immune-boosting nutrients and drugs to take before surgery, and also a list of those that you should not take 2 weeks before surgery and not resume taking until 2 weeks after surgery. I realize that you are having reconstructive surgery, but it is still surgery.
Nancy
 
 
 
Nancy
DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Oct 26 2009 at 10:05pm
Thanks Nancy.  I printed out the report and have to say that I haven't heard of most of these supplements.  I sure have a lot to learn.
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 26 2009 at 11:14pm
Dear Donna,
 
The reason that you have not heard of them, is because most doctors do not know about them. I got this link from Suzanne Somer's new book Knockout. Bill Faloon is the director and cofounder of the LIfe Extension Foundation. To quote the book..."His investigations have enabled people to access medical information not available elsewhere through the data base supplied by the Life Extension advisory board". We all have much to learn, but only if we explore all options available. This new book really opened Lori's eyes even further. She knows now that what she has pursued as to nutrition, vitamins/supplements, and most the most important addition, the biodentical hormones is what she had to do. She took control.
Nancy 
Nancy
DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote MsBliss Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 3:55am
Vitamin D on an empty stomach?  Not with food?  Are you sure?
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Post Options Post Options   Thanks (0) Thanks(0)   Quote dmwolf Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 10:17am
I know Suzanne Sommers was good as Chrissy on Three's Company, but is that really credential enough to believe everything in her book?  ;)

-d (ducking)
DX 2/08@43 stg II IDC; gr2,0 nodes. Neoadj chemo, first ACx2 (fail) then CarboTaxotereX6(better). Lump, Rads done 11/08; Clodronate. False alarm queen: PetCT lung & TM marker. NED. PBM w/recon 9/10.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote krisa Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 11:27am
I saw a headline that said Suzanne had been diagnosed by six different doctors,  who told her last November, that cancer was throughout her body.  According to her, they were all wrong.  no further explanation in the article as to why these doctors gave her this false diagnosis.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote unklez Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 11:33am
I don't mean to scare anyone but cancer is throughout EVERYONE's body. The healthy cells and immune system keeps the cancer in check. That's all. so Suzanne Sommers was not lying......

Wife Dx: Jul/09. Age: 37. Size: 3cm. BRCA: -ve. Lumpectomy: Aug/09. Micromet 1/9 node. Chemo Start: Sep/09. E5103. DD ACB-> DD Abraxane (Taxol reaction). Zometa (S0307). Canadian Fraction Rads.
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 12:28pm
MsBliss,
 
Article on D3.
Nancy
 
 
 
Nancy
DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote Nancy Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 1:05pm
Dear Krisa and Denise,
 
Yes Suzanne was misdiagnosed, and her account of this is in the book Knockout. This is the Alternative Treatment support thread, and hopefully soon to be a forum, where we can start new topics, instead of just one continuous thread. A forum where those choosing treatments other than conventional treatments can discuss their options freely, while still supporting women like my daughter Lori and many others, who did choose a mastectomy, chemo, and rads, and are now choosing alternative treatments as opposed to conventional medicine, to help restore their health.
 
Suzanne Somers wrote the book, but there are many many interviews with doctors in the field of alternative medicine, traditional medicine, oncologists, scientists, laypersons, and antiaging specialists.
Nancy
 
 
 
 
Nancy
DD Lori dx TNBC June 13,2007
Lumpectomy due to incorrect dx of a cyst
mastectomy July 6 2007
chemo ACT all 3 every 3 weeks 6 tx Aug-Nov
28 rads ended Jan 2008
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Post Options Post Options   Thanks (0) Thanks(0)   Quote mainsailset Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 3:02pm
In what I've read over at the VitD Council and elsewhere the D3 is fat soluable and should be taken with meals. The link you're referring to Nancy is specific to Catracal only, not the D but when you go to this link   http://www.citracal.com/Product/Plus_Heart_Health.aspx
The Citracal w/D they specify should be taken with meals. I believe that the confusion develops on which kind of calcium you are taking. The back of my bottle says to take the gel caps "At Mealtime"
 
dx 7/08 TN 14x6.5x5.5 cm tumor

3 Lymph nodes involved, Taxol/Sunitab+AC, 5/09 dbl masectomy, path 2mm tumor removed, lymphs all clear, RAD 32 finished 9/11/09. 9/28 CT clear 10/18/10 CT clear
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Post Options Post Options   Thanks (0) Thanks(0)   Quote 123Donna Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 6:34pm
My D3 bottle says to take with a meal.  The Citracel Calcium Citrate with Vitamin D bottle says absorbed with or without food.  I take them with my meals.
DX IDC TNBC 6/09 age 49, Stage 1,Grade 3, 1.5cm,0/5Nodes,KI-67 48%,BRCA-,6/09bi-mx, recon, T/C X4(9/09)
11/10 Recur IM node, Gem,Carb,Iniparib 12/10,MRI NED 2/11,IMRT Radsx40,CT NED11/13,MRI NED3/15

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Post Options Post Options   Thanks (0) Thanks(0)   Quote unklez Quote  Post ReplyReply Direct Link To This Post Posted: Oct 27 2009 at 6:43pm
My personal view is that one should strive to get all vitamins, enzymes, minerals etc directly from their natural sources. Failing that, the supplements should be taken with the meals.....

Wife Dx: Jul/09. Age: 37. Size: 3cm. BRCA: -ve. Lumpectomy: Aug/09. Micromet 1/9 node. Chemo Start: Sep/09. E5103. DD ACB-> DD Abraxane (Taxol reaction). Zometa (S0307). Canadian Fraction Rads.
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